Intermediates

Methyl 5-bromo-2-chloroisonicotinate

  • CAS No.886365-28-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Methyl 5-bromo-2-chloroisonicotinate (CAS 886365-28-2) is a key building block for pharmaceutical organic synthesis, available in bulk quantities with certified analysis.

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Product Technical Details

Product Overview

Methyl 5-bromo-2-chloroisonicotinate is a sophisticated halogenated pyridine derivative designed for advanced organic synthesis applications. As a critical building block, this compound features a unique substitution pattern that enables versatile chemical transformations. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for pharmaceutical research and development projects requiring precise molecular architecture.

We understand the importance of consistency in chemical manufacturing. Therefore, every batch of Methyl 5-bromo-2-chloroisonicotinate undergoes rigorous quality control testing to meet international standards. This commitment to quality ensures reliable performance in downstream reactions, minimizing variability in your synthesis routes.

Technical Specifications

ParameterValue
Product NameMethyl 5-bromo-2-chloroisonicotinate
CAS Number886365-28-2
Molecular FormulaC7H5BrClNO2
Molecular Weight250.477
AppearanceOff-white crystalline powder
Assay≥98.0%

Physical and Chemical Properties

PropertySpecification
Density1.7±0.1 g/cm3
Boiling Point286.5±35.0 °C at 760 mmHg
Flash Point127.1±25.9 °C
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.569

Industrial Applications

This intermediate serves as a vital precursor in the synthesis of complex pharmaceutical agents and agrochemical compounds. The presence of both bromine and chlorine substituents on the pyridine ring allows for selective cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings. Chemists utilize this versatility to construct diverse molecular frameworks essential for drug discovery pipelines.

Furthermore, the ester functionality provides additional handles for hydrolysis or amidation reactions. This multifunctionality makes Methyl 5-bromo-2-chloroisonicotinate a valuable asset in medicinal chemistry laboratories aiming to optimize lead compounds efficiently.

Quality Assurance and Safety

Our production facility adheres to strict safety and quality protocols. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing purity metrics and impurity profiles. Proper handling procedures are recommended to maintain product integrity. Users should employ standard laboratory safety equipment, including gloves and eye protection, when handling this chemical substance.

Packaging and Storage

To ensure stability during transit and storage, the product is packaged in secure 25 kg drums. Custom packaging solutions are available upon request to meet specific logistical requirements. Storage should be maintained in a cool, ventilated area away from direct sunlight and moisture. Adhering to these storage guidelines preserves the chemical stability and extends the shelf life of the material.

Why Choose Our Supply

  • Global manufacturing capabilities with consistent supply chains
  • Competitive bulk pricing structures for large-scale projects
  • Dedicated technical support for synthesis optimization
  • Fast delivery times to minimize project delays
  • Strict compliance with international shipping regulations