Intermediates

Methyl 5-Fluoro-2-Methyl-3-Nitrobenzoate

  • CAS No.697739-03-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate for Rucaparib synthesis. Available in bulk with strict quality control and global shipping.

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Product Technical Details

Product Overview

Methyl 5-Fluoro-2-Methyl-3-Nitrobenzoate is a specialized organic compound serving as a critical building block in the pharmaceutical industry. This fine chemical intermediate is primarily utilized in the multi-step synthesis of advanced therapeutic agents, including PARP inhibitors such as Rucaparib. Our manufacturing process ensures consistent molecular integrity and high purity levels, making it an ideal choice for research laboratories and large-scale production facilities focused on oncology drug development.

The compound features a distinct benzoate structure substituted with fluoro, methyl, and nitro groups, which provides the necessary reactivity for downstream coupling reactions. We adhere to strict Good Manufacturing Practices to guarantee that every batch meets the rigorous demands of modern medicinal chemistry. Our facility is equipped with state-of-the-art analytical instruments to verify composition and minimize impurities.

Chemical Specifications

Quality control is paramount in the production of pharmaceutical intermediates. We employ high-performance liquid chromatography and other advanced techniques to validate the identity and purity of each lot. The following table outlines the key technical parameters for this product.

Parameter Specification
Chemical Name Methyl 5-Fluoro-2-Methyl-3-Nitrobenzoate
CAS Number 697739-03-0
Molecular Formula C9H8FNO4
Molecular Weight 213.16 g/mol
Purity (HPLC) ≥98.0%
Appearance White to grey powder
Packaging 25 kg/drum or customized

Industrial Applications

This intermediate plays a pivotal role in the construction of complex heterocyclic systems found in targeted cancer therapies. Its specific substitution pattern allows for selective functionalization, which is essential for achieving the desired biological activity in the final drug product. Beyond oncology, similar fluorinated benzoates are often explored in agrochemical and material science research due to their stability and reactivity profile.

  • Key precursor for PARP inhibitor synthesis pathways.
  • Suitable for nucleophilic aromatic substitution reactions.
  • Compatible with various esterification and reduction processes.
  • Used in custom organic synthesis for drug discovery programs.

Quality Assurance And Packaging

We understand the importance of supply chain reliability for pharmaceutical manufacturers. Each shipment is accompanied by a comprehensive Certificate of Analysis detailing test results against internal specifications. Our packaging solutions are designed to protect the material from moisture and light during transit, ensuring stability upon arrival. We offer flexible logistics options to support global distribution needs while maintaining compliance with international shipping regulations for chemical goods.

Storage recommendations include keeping the container tightly closed in a cool, ventilated area away from incompatible substances. Our technical support team is available to assist with handling guidelines and safety data information. Partner with us for a reliable source of high-quality chemical intermediates that drive innovation in healthcare.