Intermediates

Methyl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate

  • CAS No.900186-90-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate essential for Vorapaxar Sulfate synthesis. Available in bulk quantities with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

Methyl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate is a specialized organic compound recognized for its critical role in the pharmaceutical manufacturing sector. As a key building block, this chemical serves as a vital precursor in the synthesis of advanced therapeutic agents, specifically contributing to the production of Vorapaxar Sulfate. Our facility ensures that every batch meets rigorous international standards, providing researchers and manufacturers with a reliable source of high-quality intermediates.

The structural integrity of this acrylate derivative is maintained through precise synthetic protocols. The presence of the nitro group and the specific stereochemistry of the E-isomer are crucial for downstream reaction efficiency. We understand that consistency in molecular structure directly impacts the yield and purity of the final active pharmaceutical ingredient. Therefore, our production lines are optimized to minimize impurities and maximize batch-to-batch reproducibility.

Technical Specifications

To guarantee performance in complex synthesis routes, we adhere to strict analytical parameters. The following table outlines the standard specifications for this product as supplied from our manufacturing plant.

ParameterSpecification
Chemical NameMethyl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate
CAS Number900186-90-5
Molecular FormulaC10H13NO4
Molecular Weight211.22 g/mol
AppearanceWhite powder
Assay (Purity)≥98.0%
Packaging25 kg/drum or customized

Industrial Applications

This compound is primarily utilized as an intermediate in the pharmaceutical industry. Its most notable application is in the manufacturing process of Vorapaxar Sulfate, an antiplatelet medication used to reduce thrombotic cardiovascular events. The high purity level of our intermediate ensures that the subsequent coupling and functionalization reactions proceed with optimal efficiency, reducing waste and improving overall process economics.

Beyond its primary use, this nitrocyclohexene derivative may serve as a valuable building block in organic synthesis research. Chemists utilize such structures to explore new reaction pathways or develop analogues for structure-activity relationship studies. The stability of the ester and nitro functionalities allows for diverse chemical transformations under controlled conditions.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing philosophy. Each production lot undergoes comprehensive testing using advanced chromatographic and spectroscopic methods. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for identity, purity, and physical properties. This transparency allows our clients to maintain their own quality management systems without interruption.

  • Strict quality control protocols at every production stage.
  • Comprehensive documentation including COA and MSDS.
  • Flexible packaging solutions to meet logistical requirements.
  • Global shipping capabilities with secure handling.

Proper storage is essential to maintain the chemical stability of this product. It should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent degradation. Under recommended storage conditions, the product retains its specified properties for an extended period. For large-scale industrial requirements, we offer bulk pricing and customized packaging options to suit your specific manufacturing needs.