Methyl Pentafluoropropionate
- CAS No.378-75-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Methyl pentafluoropropionate (CAS 378-75-6) is a high-purity fluorinated ester intermediate widely used in pharmaceutical R&D and advanced material synthesis.
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Product Overview
Methyl pentafluoropropionate (CAS 378-75-6) is a versatile fluorinated organic ester serving as a critical building block in modern synthetic chemistry. With its fully substituted pentafluoroalkyl chain, this compound offers exceptional electron-withdrawing properties and metabolic stability, making it highly valuable in the design of novel bioactive molecules and functional materials. As a specialty fluorochemical intermediate, it supports innovation across pharmaceutical research, agrochemical development, and advanced polymer science.
Specifications
| Molecular Formula | C4H3F5O2 |
|---|---|
| Molecular Weight | 168.06 g/mol |
| Appearance | Transparent colorless liquid |
| Density | 1.393 g/mL at 25 °C (lit.) |
| Boiling Point | 61 °C at 739 mm Hg (lit.) |
| Flash Point | 42 °F |
| Refractive Index | n20/D 1.288 (lit.) |
| Storage Conditions | Store in a flammables area under inert atmosphere, away from heat and ignition sources. |
Industrial Applications
This fluorinated ester is primarily employed as a synthetic intermediate in the preparation of complex pharmaceutical APIs and novel agrochemical candidates. Its robust C–F bonds enhance lipophilicity and resistance to oxidative metabolism, key attributes in lead optimization. Additionally, methyl pentafluoropropionate finds use in the development of fluorinated monomers for specialty polymers with improved thermal and chemical resistance. Our company leverages integrated fluorochemical expertise—from raw material sourcing to quality-controlled production—to deliver consistent, high-purity batches tailored for demanding R&D and scale-up applications.
- Enables efficient introduction of pentafluoropropyl motifs into target molecules
- Suitable for nucleophilic substitution and cross-coupling transformations
- Supports one-stop fluorochemical solutions from concept to commercialization
