Methyl Pyridine-4-Carboxylate
- CAS No.2459-09-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Methyl Pyridine-4-Carboxylate (CAS 2459-09-8) supplied as a clear liquid for pharmaceutical synthesis. Ideal intermediate for antihistamine production with strict quality control.
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Product Overview
Methyl Pyridine-4-Carboxylate, frequently referred to in industrial contexts as Methyl Isonicotinate, stands as a vital chemical building block within the pharmaceutical and fine chemical sectors. This organic compound features a pyridine ring substituted with a methyl ester functional group at the fourth position, offering exceptional reactivity for various synthetic transformations. Our manufacturing facility specializes in producing this intermediate under rigorous quality management systems, ensuring that every batch meets the stringent requirements necessary for downstream drug synthesis. The material is supplied as a clear liquid, ranging from orange to brown in color, indicating its high concentration and purity levels suitable for immediate use in complex organic reactions.
The significance of this compound lies in its role as a precursor for advanced therapeutic agents. By maintaining strict control over the esterification process, we guarantee minimal impurity profiles, which is critical when synthesizing active pharmaceutical ingredients (APIs). Our production capabilities are scaled to support both research-scale requirements and large-scale industrial manufacturing, providing flexibility to clients across the global supply chain.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 2459-09-8 |
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.14 g/mol |
| Appearance | Clear orange to brown liquid |
| Purity | ≥99.0% |
| Boiling Point | 207-209 °C |
| Density | 1.161 g/mL at 25 °C |
| Refractive Index | n20/D 1.512 |
| Heavy Metals | <10 PPM |
| Residue on Ignition | <0.1% |
Industrial Applications
The primary application of Methyl Pyridine-4-Carboxylate is in the synthesis of antihistamine medications, specifically serving as a key intermediate in the production of Fexofenadine hydrochloride. Its chemical structure allows for efficient coupling and substitution reactions, making it indispensable for medicinal chemists developing non-sedating antihistamines. Beyond pharmaceuticals, this compound is utilized in agrochemical research and the development of specialized fine chemicals where pyridine derivatives are required for their unique electronic and steric properties. The high purity grade ensures that there is minimal carryover of impurities into the final API, thereby reducing purification costs and improving overall yield in multi-step synthesis routes.
Quality Assurance And Storage
Quality consistency is the cornerstone of our supply service. Every shipment of Methyl Pyridine-4-Carboxylate is accompanied by a comprehensive Certificate of Analysis (COA) that verifies all critical physical and chemical parameters, including boiling point, refractive index, and heavy metal content. We employ advanced chromatographic techniques to monitor purity levels throughout the manufacturing process. For storage, we recommend keeping the material in a cool, dry, and well-closed container, protected from moisture and strong light or heat sources to maintain stability over time. Our logistics network supports global delivery, typically packaging the product in 25kg cardboard drums or according to specific customer requirements, ensuring safe transit and compliance with international shipping regulations.
