N-(4-Nitrophenethyl)acetamide
- CAS No.6270-07-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-(4-Nitrophenethyl)acetamide (CAS 6270-07-1) designed for pharmaceutical synthesis. Reliable supply for Dofetilide production with strict quality control.
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Product Overview
N-(4-Nitrophenethyl)acetamide, identified by CAS number 6270-07-1, stands as a critical chemical building block within the pharmaceutical industry. This specialized organic compound serves as a key intermediate in the synthesis of complex therapeutic agents, most notably contributing to the production pipeline of antiarrhythmic medications. Our manufacturing process ensures that each batch meets rigorous international standards for chemical purity and structural integrity, making it an ideal choice for research and development laboratories as well as large-scale production facilities.
The molecular structure features a nitro group positioned on the phenethyl backbone, acetylated to enhance stability and reactivity during subsequent synthetic steps. This specific configuration allows for precise chemical transformations required in modern medicinal chemistry. As a dedicated supplier, we understand the importance of consistency in molecular weight and functional group performance, which is why our quality assurance protocols are designed to minimize variability and maximize yield in downstream applications.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | N-(4-Nitrophenethyl)acetamide |
| CAS Number | 6270-07-1 |
| Molecular Formula | C10H12N2O3 |
| Molecular Weight | 208.214 g/mol |
| Appearance | Light yellow powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 140°C |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 451.4±28.0 °C at 760 mmHg |
| Flash Point | 226.8±24.0 °C |
| Refractive Index | 1.551 |
Industrial Applications
The primary application of this compound lies in its role as a precursor for Dofetilide, a class III antiarrhythmic agent used in the management of atrial fibrillation and flutter. The high purity level of our N-(4-Nitrophenethyl)acetamide ensures that the subsequent synthesis steps proceed with minimal impurity carryover, which is crucial for meeting regulatory requirements in pharmaceutical manufacturing. Beyond this specific API, the compound is valuable in organic synthesis research where nitrophenethyl derivatives are required for exploring structure-activity relationships.
Chemists and process engineers utilize this intermediate for its reliable reactivity profile. The acetylated amine group provides protection during various reaction conditions, while the nitro group offers a versatile handle for reduction or substitution reactions. This dual functionality makes it a versatile tool in the synthesis of diverse heterocyclic systems and pharmacologically active molecules. Our supply chain supports both pilot-scale experiments and commercial manufacturing needs.
Quality Assurance and Handling
We maintain a robust quality management system to guarantee the consistency of every shipment. Each drum is accompanied by a comprehensive Certificate of Analysis (COA) that details the specific test results for identity, purity, and physical properties. Our packaging consists of 25 kg drums, designed to protect the material from moisture and physical damage during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements.
- Strict quality control testing at every production stage
- Stable chemical properties for long-term storage
- Compliant with international safety and shipping regulations
- Technical support available for synthesis optimization
For optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. Proper handling procedures, including the use of personal protective equipment, are recommended to ensure safety during weighing and transfer operations. By choosing our facility as your partner, you gain access to a reliable source of high-performance chemical intermediates backed by decades of industry expertise.
