(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide
- CAS No.863127-76-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity pharmaceutical intermediate used in the synthesis of kinase inhibitors. Available in bulk quantities with comprehensive quality documentation.
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Product Overview
(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is a specialized organic compound primarily utilized as a critical intermediate in the pharmaceutical industry. This chemical building block plays an essential role in the multi-step synthesis of advanced kinase inhibitors, specifically serving as a precursor in the manufacturing process of Dasatinib. Our facility ensures that every batch meets rigorous international standards for purity and consistency, supporting global research and production needs.
As a dedicated manufacturer, we understand the importance of supply chain reliability for active pharmaceutical ingredient (API) synthesis. This product is synthesized using advanced organic chemistry techniques to ensure minimal impurity profiles, facilitating downstream reactions with high efficiency. The compound is characterized by its stable chemical structure and favorable reactivity, making it an ideal choice for complex medicinal chemistry applications.
Chemical Properties And Specifications
The physical and chemical characteristics of this intermediate are tightly controlled to ensure performance in subsequent synthetic steps. The material typically presents as a light yellow to light brown powder, indicating high stability under standard storage conditions. Our quality control laboratory employs high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to verify structural integrity and purity levels.
| Parameter | Specification |
|---|---|
| CAS Number | 863127-76-8 |
| Molecular Formula | C12H14ClNO2 |
| Molecular Weight | 239.70 g/mol |
| Purity | ≥99.0% |
| Appearance | Light yellow or light brown powder |
| Moisture Content | ≤0.02% |
| Density | 1.197 g/cm3 |
| Boiling Point | 386.5°C at 760 mmHg |
Industrial Applications
This acrylamide derivative is predominantly employed in the pharmaceutical sector as a key building block. Its primary application lies in the synthesis of tyrosine kinase inhibitors, which are vital in modern oncology research and therapeutic development. By providing a high-quality intermediate, we enable our partners to maintain robust production schedules for downstream API manufacturing. The chemical structure allows for specific functional group transformations required in the final drug substance assembly.
Beyond standard pharmaceutical use, this compound may also serve as a reference standard in analytical laboratories or as a research chemical for investigating structure-activity relationships in medicinal chemistry programs. Our team supports custom synthesis requests for clients requiring specific modifications or scaled-up production runs to meet clinical trial demands.
Quality Assurance And Storage
We adhere to strict quality management systems to guarantee product safety and efficacy. Each shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. To maintain optimal stability, the product should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed to protect against moisture absorption and exposure to strong light or heat sources.
Packaging options include 25kg cardboard drums or customized solutions based on client logistics requirements. We prioritize safe handling procedures and provide comprehensive safety data sheets (SDS) with every order. Our global distribution network ensures timely delivery while maintaining the integrity of the chemical throughout transit. For technical inquiries or bulk pricing requests, our sales team is available to provide detailed support.
