N-[3-(methylamino)propyl]oxolane-2-carboxamide
- CAS No.81403-67-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity N-[3-(methylamino)propyl]oxolane-2-carboxamide (CAS 81403-67-0) serves as a critical pharmaceutical intermediate for Alfuzosin synthesis, available in bulk quantities with full quality documentation.
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Product Overview
N-[3-(methylamino)propyl]oxolane-2-carboxamide is a specialized organic compound characterized by its oxolane ring structure and amide functionality. This chemical serves as a vital building block in the pharmaceutical industry, specifically designed for complex synthesis pathways requiring high structural integrity and purity. Our manufacturing facility produces this intermediate under strict quality control protocols to ensure consistency across batches, meeting the rigorous demands of modern drug development.
The compound features a methylaminopropyl chain attached to the oxolane carboxamide core, providing unique reactivity profiles suitable for downstream chemical transformations. As a key precursor, it facilitates the construction of active pharmaceutical ingredients (APIs) where precise molecular architecture is essential for therapeutic efficacy.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | N-[3-(methylamino)propyl]oxolane-2-carboxamide |
| CAS Number | 81403-67-0 |
| Molecular Formula | C9H18N2O2 |
| Molecular Weight | 186.25 g/mol |
| Purity | ≥97% |
| Density | 1.045 g/cm3 |
| Boiling Point | 380.81°C at 760 mmHg |
| Flash Point | 184.11°C |
| Refractive Index | 1.477 |
Industrial Applications
This intermediate is primarily utilized in the synthesis of Alfuzosin hydrochloride, a well-known pharmaceutical agent. The high purity grade ensures minimal impurity carryover into the final API, which is critical for regulatory compliance and patient safety. Chemists value this material for its stability during reaction conditions and its compatibility with various synthetic routes involving amide bond formation and heterocyclic modifications.
Beyond its primary application, this oxolane derivative finds utility in research and development settings where novel therapeutic candidates are explored. Its structural features allow for diverse functionalization, making it a versatile tool for medicinal chemistry teams aiming to optimize lead compounds.
Quality Assurance and Storage
Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity levels. We provide a Certificate of Analysis (COA) with each shipment, detailing all relevant quality parameters. Our production processes adhere to international standards, ensuring that the material is free from unwanted contaminants.
For optimal stability, store this product in a tightly closed container within a cool, dry, and well-ventilated area. Protect from moisture and incompatible substances to maintain chemical integrity over time. Proper handling procedures should be followed according to standard safety data sheets to ensure workplace safety.
Supply and Packaging
We offer flexible packaging options to suit diverse operational needs, typically supplying in 25kg cardboard drums or customized configurations based on client requirements. As a global manufacturer, we maintain robust supply chains to deliver bulk quantities reliably. Contact our sales team for current bulk pricing, lead times, and custom synthesis inquiries.
