Intermediates

N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline

  • CAS No.70627-52-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline (CAS 70627-52-0) designed for pharmaceutical synthesis. Reliable intermediate for Ezetimibe production with strict QC.

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Product Technical Details

Product Overview

N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline is a specialized organic compound widely recognized in the pharmaceutical industry for its critical role in the synthesis of lipid-lowering agents. As a key building block, this chemical intermediate facilitates the construction of complex molecular structures required for modern therapeutic drugs. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and development teams as well as large-scale production facilities.

This compound features a unique structural arrangement combining a benzyloxy group with a fluoroaniline moiety through an imine linkage. This specific configuration provides the necessary reactivity and stability required for downstream synthetic transformations. We prioritize safety and compliance in all production stages, adhering to international chemical management standards to guarantee product integrity.

Technical Specifications

ParameterSpecification
CAS Number70627-52-0
Chemical NameN-(4-(Benzyloxy)benzylidene)-4-fluoroaniline
Molecular FormulaC20H16FNO
Molecular Weight305.35 g/mol
AppearanceLight yellow flaky crystal
Purity≥99.0%
Melting Point136-138°C
Boiling Point455.2°C at 760 mmHg
Density1.07 g/cm3

Industrial Applications

The primary application of N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline lies in the pharmaceutical sector, specifically serving as a crucial intermediate in the synthesis of Ezetimibe. Ezetimibe is a well-known medication used to lower cholesterol levels by inhibiting the absorption of cholesterol from the intestine. The precision required in producing this intermediate directly impacts the efficacy and safety of the final pharmaceutical product.

Beyond its role in cholesterol management drugs, this chemical serves as a versatile building block in organic synthesis. Researchers utilize its reactive imine group and aromatic systems to develop novel compounds with potential biological activities. Our supply chain supports both pilot-scale experiments and commercial manufacturing needs, ensuring seamless integration into your production workflow.

Quality Assurance and Storage

Quality control is paramount in our operations. Each batch of N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing purity levels and physical properties to ensure compliance with your internal standards.

  • Strict quality monitoring at every production stage.
  • Advanced testing protocols for purity verification.
  • Documentation support including COA and MSDS.
  • Custom packaging solutions available upon request.

Proper storage is essential to maintain the stability of this chemical. It should be stored in a cool and dry well-closed container, protected from moisture and strong light or heat sources. Under recommended conditions, the product maintains its specified properties over extended periods. We offer flexible packing options, typically 25kg cardboard drums, but can accommodate specific customer requirements to optimize logistics and handling safety.