N-(4-Cyanophenyl)guanidine
- CAS No.5637-42-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-(4-Cyanophenyl)guanidine is a critical pharmaceutical intermediate used in the synthesis of advanced antiretroviral APIs. We offer bulk quantities with strict quality control and global logistics support.
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Product Overview
N-(4-Cyanophenyl)guanidine is a highly specialized organic compound characterized by its unique guanidine functional group attached to a cyanophenyl ring. This chemical structure serves as a vital building block in the pharmaceutical industry, particularly within the realm of medicinal chemistry focused on antiretroviral therapies. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for large-scale synthetic operations.
As a key precursor, this compound facilitates the construction of complex molecular architectures required for next-generation healthcare solutions. The stability of the nitrile group combined with the reactivity of the guanidine moiety allows for versatile synthetic routes, enabling chemists to develop efficient pathways for active pharmaceutical ingredient (API) production. We are committed to supplying this material with full traceability and comprehensive documentation.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 5637-42-3 |
| Molecular Formula | C8H8N4 |
| Molecular Weight | 160.176 g/mol |
| Appearance | White Crystal |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 205-215°C |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 316.6±44.0 °C at 760 mmHg |
| Flash Point | 145.3±28.4 °C |
Industrial Applications
This intermediate is primarily utilized in the synthesis of sophisticated antiretroviral agents, including but not limited to Etravirine and Rilpivirine. These final APIs are essential components in the treatment management of viral infections. The high purity level of our N-(4-Cyanophenyl)guanidine ensures minimal impurity carry-over into subsequent reaction steps, thereby optimizing yield and reducing downstream purification costs.
Beyond specific API synthesis, this compound finds utility in broader organic synthesis projects where a substituted guanidine structure is required. Researchers value this material for its reliable performance in coupling reactions and cyclization processes. Our technical team supports clients with guidance on optimal storage and handling to maintain chemical integrity throughout the production lifecycle.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Each production lot undergoes strict analytical testing using High-Performance Liquid Chromatography (HPLC) and melting point determination to verify compliance with specified parameters. We provide a Certificate of Analysis (COA) with every shipment, detailing the exact composition and test results.
- Packaged in 25 kg drums or customized according to client requirements.
- Stored in a cool, ventilated warehouse away from direct sunlight and moisture.
- Handled with appropriate personal protective equipment (PPE) to ensure safety.
- Global shipping capabilities with secure logistics partners.
We understand the critical nature of supply chain reliability in pharmaceutical manufacturing. Our facility maintains ample stock levels to accommodate urgent orders while adhering to all regulatory compliance standards for chemical export. Partner with us for a dependable source of high-quality pharmaceutical intermediates.
