Intermediates

N-Benzyloxycarbonyl-3-Fluoro-4-Morpholinoaniline

  • CAS No.168828-81-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of linezolid. Available in bulk quantities with strict quality control and comprehensive documentation.

Request Bulk Pricing

Product Technical Details

Product Overview

N-Benzyloxycarbonyl-3-Fluoro-4-Morpholinoaniline is a specialized pharmaceutical intermediate designed for advanced organic synthesis within the medicinal chemistry sector. This compound features a robust chemical structure incorporating a benzyloxycarbonyl protecting group, a fluorine substituent, and a morpholine ring, making it highly valuable for constructing complex therapeutic agents. Our facility produces this material under stringent quality management systems to ensure consistency and reliability for downstream processing.

As a key building block, this chemical plays a critical role in the production pipeline of specific antibiotic formulations. The presence of the morpholino group enhances solubility and bioavailability profiles in final active pharmaceutical ingredients. We prioritize safety and compliance in all manufacturing stages, ensuring that every batch meets international regulatory standards for chemical intermediates.

Technical Specifications

Our production process utilizes advanced purification techniques to achieve high assay values suitable for sensitive synthetic routes. The physical properties are tightly controlled to facilitate easy handling and integration into various reaction conditions. Below are the detailed technical parameters for this product.

ParameterValue
CAS Number168828-81-7
Molecular FormulaC18H19FN2O3
Molecular Weight330.353 g/mol
AppearanceWhite to off-white powder
Assay≥98.0%
Melting Point123.0 to 127.0 °C
Density1.3±0.1 g/cm3
Boiling Point451.8±45.0 °C at 760 mmHg
Flash Point227.0±28.7 °C

Industrial Applications

This intermediate is primarily utilized in the pharmaceutical industry for the synthesis of linezolid and related oxazolidinone antibiotics. The high purity level ensures minimal impurity carryover into the final active pharmaceutical ingredient, which is crucial for regulatory approval and patient safety. Chemists value this compound for its reactivity profile and stability during multi-step synthesis sequences.

Beyond antibiotic synthesis, this molecule serves as a versatile building block in medicinal chemistry research and development. It is suitable for exploring structure-activity relationships in new drug discovery programs targeting bacterial infections. Our supply chain supports both large-scale commercial manufacturing and small-scale laboratory research needs.

Quality Assurance and Packaging

Quality is the cornerstone of our operation. Each batch undergoes rigorous testing using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy to confirm identity and purity. We provide a comprehensive Certificate of Analysis with every shipment, detailing all relevant test results and compliance data.

Standard packaging consists of 25 kg drums lined with protective materials to prevent moisture absorption and contamination during transit. Custom packaging solutions are available upon request to meet specific logistical requirements. Storage recommendations include keeping the product in a cool, ventilated area away from direct sunlight and incompatible substances to maintain stability over extended periods.

Why Choose Our Supply

  • Consistent high purity levels exceeding 98 percent
  • Reliable global shipping and logistics support
  • Full technical documentation and regulatory compliance
  • Competitive bulk pricing for long-term partnerships
  • Dedicated customer service for technical inquiries

We are committed to supporting our partners with reliable chemical solutions that drive innovation in pharmaceutical development. Contact our sales team today to discuss your specific requirements and request a quote for N-Benzyloxycarbonyl-3-Fluoro-4-Morpholinoaniline.