N-Boc-O-Benzyl-D-serine
- CAS No.47173-80-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-Boc-O-Benzyl-D-serine (CAS 47173-80-8) is a key chiral building block for peptide synthesis and advanced pharmaceutical intermediates.
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Product Overview
N-Boc-O-Benzyl-D-serine is a protected D-serine derivative widely employed in the synthesis of complex peptides and bioactive molecules. Featuring both tert-butoxycarbonyl (Boc) and benzyl (Bzl) protecting groups, this compound offers excellent stability and selective deprotection capabilities, making it indispensable in solid-phase and solution-phase peptide chemistry. With a molecular formula of C15H21NO5 and a molecular weight of 295.33 g/mol, it ensures high reactivity and compatibility with standard coupling protocols.
Specifications
| CAS Number | 47173-80-8 |
|---|---|
| Molecular Formula | C15H21NO5 |
| Molecular Weight | 295.33 g/mol |
| Appearance | White crystalline powder |
| Purity | ≥98% (by HPLC) |
| Melting Point | 58–60 °C (lit.) |
| Density | 1.174 g/cm³ |
| Boiling Point | 456.2 °C at 760 mmHg |
| Flash Point | 229.7 °C |
| Refractive Index | 1.523 |
Industrial Applications
This chiral amino acid derivative serves primarily as a critical intermediate in the production of therapeutic peptides, protease inhibitors, and other high-value active pharmaceutical ingredients (APIs). Its orthogonal protection strategy enables precise control during multi-step syntheses, particularly in the development of neurological therapeutics and advanced organic synthesis pathways. It is not intended for direct human or veterinary use but is strictly for research and industrial-scale manufacturing under GMP-compliant environments.
- Essential building block for stereoselective peptide synthesis
- Compatible with Fmoc/Boc SPPS (solid-phase peptide synthesis) strategies
- Enables selective deprotection for sequential coupling reactions
- Supplied with full analytical documentation including COA and HPLC chromatograms
Stored at 2–8 °C in a tightly sealed container under dry, cool conditions to maintain integrity and extend shelf life. Packaging is available in 25 kg drums or customized configurations upon request.
