N-Ethylethylenediamine
- CAS No.110-72-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-Ethylethylenediamine (CAS 110-72-5), a key pharmaceutical intermediate for cephalosporin antibiotics such as Cefoperazone.
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Product Overview
N-Ethylethylenediamine (CAS 110-72-5) is a high-value aliphatic diamine widely employed as a critical building block in the synthesis of advanced pharmaceutical intermediates. With a molecular formula of C4H12N2 and a molecular weight of 88.15 g/mol, this compound features two amine functionalities that enable versatile reactivity in organic transformations, particularly in the construction of beta-lactam antibiotic scaffolds.
Specifications
| Appearance | Colorless to light yellow transparent liquid |
|---|---|
| Assay (Purity) | ≥98.0% (Typical: 99.03%) |
| Moisture | ≤0.5% (Typical: 0.07%) |
| Ethylenediamine Impurity | ≤1.0% (Typical: 0.05%) |
| Density | 0.837 g/mL at 25 °C |
| Boiling Point | 128–130 °C |
| Flash Point | 50 °F (10 °C) |
| Refractive Index | n20/D 1.439 |
Industrial Applications
As a specialized intermediate in antibiotic manufacturing, N-Ethylethylenediamine serves as an essential precursor in the production of Cefoperazone (CAS 62893-19-0), a third-generation cephalosporin with broad-spectrum activity. Its bifunctional amine structure facilitates selective acylation and cyclization steps under controlled conditions, ensuring high yield and purity in active pharmaceutical ingredient (API) synthesis.
Key advantages for industrial users include:
- Consistent batch-to-batch quality meeting stringent pharmaceutical standards
- Low moisture and minimal ethylenediamine impurity for optimized reaction efficiency
- Scalable supply suitable for GMP-compliant manufacturing environments
Handling and Storage
Store in a tightly sealed container in a cool, dry, and well-ventilated area away from heat, sparks, open flames, and direct sunlight. Due to its low flash point, appropriate fire safety measures must be observed. Keep away from strong oxidizing agents and acids to prevent hazardous reactions.
Packaging
Standard packaging is 25 kg in fiberboard drums with inner liners. Custom packaging options are available upon request to meet specific logistical or regulatory requirements.
