Intermediates

N-Methyl-1,2-benzenediamine Dihydrochloride

  • CAS No.25148-68-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity N-Methyl-1,2-benzenediamine dihydrochloride (CAS 25148-68-9), a critical intermediate for Telmisartan synthesis. Available in bulk with full COA and competitive pricing.

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Product Technical Details

Product Overview

N-Methyl-1,2-benzenediamine dihydrochloride is a specialized organic compound widely recognized for its pivotal role in the pharmaceutical industry, particularly within the synthesis of angiotensin II receptor blockers. This chemical serves as a fundamental building block in the manufacturing process of Telmisartan, a widely prescribed medication used for managing hypertension and cardiovascular conditions. Our facility ensures that every batch meets stringent quality standards, providing reliability for downstream API production.

As a leading manufacturer, we understand the critical nature of intermediate purity in final drug efficacy. Our production lines are optimized to deliver consistent molecular integrity, minimizing impurities that could affect subsequent reaction steps. The compound is characterized by its stable crystalline structure and high solubility in relevant organic solvents, making it ideal for various synthetic pathways required in modern medicinal chemistry.

Technical Specifications

ParameterValue
CAS Number25148-68-9
Chemical FormulaC7H12Cl2N2
Molecular Weight195.09 g/mol
AppearanceOff-white to pink crystalline powder
Assay (Purity)≥98.5%
Loss on Drying≤1.5%
Melting Point191°C
EINECS No.246-655-8

Industrial Applications

The primary application of this material lies in the pharmaceutical sector, specifically as a key intermediate for Telmisartan. The precision required in this synthesis demands raw materials with exceptional purity profiles. Our product supports efficient coupling reactions and ensures high yields in the final API manufacturing process. Beyond Telmisartan, this diamine derivative finds utility in research and development for novel cardiovascular therapeutics and related organic synthesis projects.

  • Essential precursor for antihypertensive drug synthesis
  • Compatible with standard industrial scaling processes
  • Supports high-efficiency reaction pathways
  • Validated for use in GMP-compliant environments

Quality Assurance and Storage

Quality control is paramount in our operations. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against specified parameters. We employ advanced analytical techniques, including HPLC and GC, to verify composition and purity levels. This commitment to quality assurance ensures that our partners receive materials that perform predictably in their manufacturing workflows.

Proper storage is essential to maintain the chemical stability of N-Methyl-1,2-benzenediamine dihydrochloride. The product should be kept in a cool, ventilated warehouse away from direct heat sources and open flames. Storage temperatures should not exceed 37°C to prevent degradation. Packaging is available in 25 kg barrels, with customization options to suit specific logistical requirements. We adhere to strict safety protocols, classifying the material under Hazard Class 6.1, ensuring safe handling and transportation globally.