N-Methyl-4-nitroaniline

Product Overview

N-Methyl-4-nitroaniline is a critical organic compound widely utilized in the pharmaceutical and chemical synthesis industries. As a specialized intermediate, it plays a pivotal role in the production of advanced therapeutic agents, including specific kinase inhibitors. Our facility manufactures this compound under strict quality control protocols to ensure consistency and reliability for downstream processing. The chemical structure features a nitro group positioned para to the amino group on the benzene ring, with a methyl substitution on the nitrogen atom, providing unique reactivity profiles suitable for complex organic transformations.

We understand the importance of purity in pharmaceutical manufacturing. Therefore, our production process is optimized to minimize impurities and by-products. This commitment to quality ensures that our clients receive a material that meets rigorous industry standards, facilitating smoother synthesis routes and higher yields in final drug substance production. Our team of chemists continuously monitors production batches to maintain the high specifications required by global regulatory bodies.

Technical Specifications

The following table outlines the key physical and chemical properties of our N-Methyl-4-nitroaniline. These parameters are verified through advanced analytical techniques including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and Karl Fischer titration to guarantee accuracy.

Industrial Applications

This compound serves primarily as a key building block in the synthesis of Nintedanib esylate, a significant pharmaceutical agent used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. Beyond this specific application, N-Methyl-4-nitroaniline is valued in organic chemistry for nitration and reduction reactions. Its stability and reactivity make it a preferred choice for researchers and industrial chemists developing new chemical entities. We support various scales of production from laboratory research to full commercial manufacturing.

• Pharmaceutical Intermediate for Kinase Inhibitors
• Organic Synthesis Building Block
• Research and Development Material
• Custom Chemical Manufacturing

Quality Assurance and Safety

Quality is the cornerstone of our manufacturing philosophy. Every batch of N-Methyl-4-nitroaniline undergoes comprehensive testing before release. We provide a Certificate of Analysis (COA) with every shipment, detailing the test results against our factory standards. Our facility adheres to international safety and environmental regulations, ensuring that our products are handled and produced responsibly. We encourage our partners to review our safety data sheets (SDS) to ensure proper handling during transportation and usage. Our quality management system is designed to trace every step of the production process.

Packaging and Storage

To maintain product integrity, our N-Methyl-4-nitroaniline is packaged in 25 kg drums, though custom packaging solutions are available upon request to suit specific logistical needs. The material should be stored in a cool, well-ventilated area away from direct sunlight and incompatible substances. Proper storage conditions help preserve the chemical stability and physical appearance of the powder over extended periods. We offer global shipping capabilities, ensuring timely delivery to our clients worldwide while maintaining compliance with international transport regulations for chemical goods. Our logistics team ensures secure handling throughout the supply chain.