N,N-Carbonyldiimidazole

Product Overview

N,N-Carbonyldiimidazole, commonly known as CDI, stands as a pivotal reagent in modern organic synthesis and pharmaceutical manufacturing. This versatile compound serves as an exceptional coupling agent, particularly valued for its efficiency in activating carboxylic acids during peptide synthesis. Our facility produces this chemical intermediate under strict quality control protocols to ensure consistent performance across various industrial applications. As a leading global manufacturer, we understand the critical need for high-purity reagents that facilitate seamless reaction pathways without introducing unwanted byproducts.

The chemical stability and reactivity profile of N,N-Carbonyldiimidazole make it a preferred choice for chemists working on complex molecular structures. Unlike some alternative coupling agents, CDI offers the advantage of generating imidazole as a byproduct, which is generally easier to remove during workup procedures. This characteristic significantly streamlines the purification process, saving time and resources in large-scale production environments. Our commitment to excellence ensures that every batch meets rigorous international standards for pharmaceutical and fine chemical applications.

Key Specifications

We maintain transparent quality standards to support our partners in research and development. The following table outlines the critical physical and chemical parameters verified through our internal quality assurance laboratory. Each shipment is accompanied by a Certificate of Analysis to guarantee compliance with the specified metrics.

Industrial Applications

The primary utility of this compound lies in its role as a dehydration coupling agent. It is extensively utilized in the synthesis of peptides, where it activates amino acids for amide bond formation. Beyond peptide chemistry, N,N-Carbonyldiimidazole finds application in the preparation of esters, anhydrides, and other carbonyl derivatives. Its ability to function under mild conditions makes it suitable for sensitive substrates that might degrade under harsher reaction environments. Researchers also employ this reagent in the synthesis of heterocycles and various pharmaceutical intermediates requiring precise activation steps.

Our clients across the pharmaceutical and agrochemical sectors rely on our supply chain for uninterrupted production schedules. Whether used in laboratory-scale discovery or kilogram-scale process development, the consistency of our product ensures reproducible results. We support our customers with technical documentation and safety data sheets to facilitate safe handling and regulatory compliance within their respective jurisdictions.

Storage and Safety

Proper storage is essential to maintain the integrity of N,N-Carbonyldiimidazole. The material should be kept in a cool, ventilated area away from moisture and incompatible substances. Exposure to humidity can lead to hydrolysis, reducing the effective potency of the reagent. We recommend sealing containers tightly after each use and storing them in a dry environment. Our packaging options include standard 25 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. Safety protocols dictate the use of appropriate personal protective equipment during handling to prevent irritation. By adhering to these guidelines, users can maximize the shelf life and performance of this valuable chemical intermediate.