Intermediates

N,N-Dimethyl-2-morpholin-4-ylethanamine

  • CAS No.4385-05-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity N,N-Dimethyl-2-morpholin-4-ylethanamine (CAS 4385-05-1), a key building block for advanced organic and pharmaceutical synthesis.

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Product Technical Details

Product Overview

N,N-Dimethyl-2-morpholin-4-ylethanamine is a high-value tertiary amine featuring a morpholine ring linked to a dimethylaminoethyl group. With the molecular formula C8H18N2O and a molecular weight of 158.24 g/mol, this compound serves as a versatile intermediate in the development of complex active pharmaceutical ingredients (APIs) and fine chemical syntheses. Its bifunctional structure—combining both aliphatic amine and heterocyclic ether moieties—enables diverse reactivity profiles, making it particularly useful in multi-step synthetic routes requiring selective functionalization or as a ligand precursor in catalytic systems.

Specifications

Molecular FormulaC8H18N2O
Molecular Weight158.24 g/mol
CAS Number4385-05-1
AppearanceWhite powder
Purity≥98.0%
Moisture Content0.25%
Impurity0.3%
Density0.925 g/mL at 25 °C
Boiling Point93–94 °C at 20 mm Hg
Refractive Indexn20/D 1.4582
Flash Point168 °F

Industrial Applications

This compound is primarily employed as a specialty intermediate in the pharmaceutical and agrochemical industries. Its structural features support its use in the synthesis of bioactive molecules targeting neurological, metabolic, and inflammatory pathways. Additionally, it functions as a building block in the preparation of chelating agents, surfactants, and corrosion inhibitors. Due to its high purity and consistent quality, it is suitable for GMP-compliant manufacturing environments where reproducibility and traceability are critical.

  • Key intermediate for complex pharmaceutical APIs
  • Enables modular synthesis in medicinal chemistry campaigns
  • Compatible with standard amine-handling protocols
  • Supplied with full analytical documentation including COA

Handling and Storage

Store in a tightly sealed container in a cool, dry, and well-ventilated area, away from oxidizing agents and strong acids. Use appropriate personal protective equipment during handling. Standard industrial hygiene practices are recommended.