N,N-Dimethylacetamide
- CAS No.127-19-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N,N-Dimethylacetamide (CAS 127-19-5) serving as a versatile solvent and key pharmaceutical intermediate for global industrial applications.
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Product Overview
N,N-Dimethylacetamide (DMAc) represents a critical component in modern chemical synthesis and polymer processing. As a polar aprotic solvent, it exhibits exceptional solvating power for a wide range of organic compounds and polymers. Our facility produces high-purity grades suitable for demanding pharmaceutical intermediates and advanced material manufacturing. The chemical stability and miscibility profile of DMAc make it an indispensable reagent for complex organic transformations and extraction processes.
We prioritize rigorous quality control to ensure every batch meets international standards for purity and impurity profiles. This commitment supports downstream manufacturers in achieving consistent reaction yields and product quality. Our production capabilities allow for scalable supply to meet global industrial demands while maintaining strict safety and environmental compliance protocols.
Key Physical Properties
The physical characteristics of N,N-Dimethylacetamide contribute significantly to its utility in industrial settings. It presents as a transparent colorless liquid with a distinct amide odor. The high boiling point allows for reactions to proceed at elevated temperatures without significant solvent loss. Additionally, its low freezing point ensures handling convenience across various climatic conditions.
Thermal stability is a defining feature, enabling use in processes requiring sustained heat exposure. The density and refractive index values are tightly controlled during manufacturing to guarantee batch-to-batch consistency. Low water content is maintained through advanced distillation techniques, which is crucial for moisture-sensitive synthetic routes. These properties collectively enhance process efficiency and reduce downstream purification burdens.
Industrial Applications
DMAc serves diverse roles across multiple high-value sectors. In the pharmaceutical industry, it acts as a primary solvent for the synthesis of active pharmaceutical intermediates. Its ability to dissolve both polar and non-polar compounds facilitates complex coupling reactions and crystallization steps. The low basicity and acidity levels prevent unwanted side reactions during sensitive catalytic processes.
- Polymer Processing: Essential solvent for spinning spandex, aramid, and acrylic fibers.
- Electronics: Used in the production of high-grade polyimide films for flexible circuits.
- Chemical Synthesis: Acts as a reaction medium for acetylation and alkylation processes.
- Extraction: Effective agent for separating organic compounds from aqueous mixtures.
Our product supports the manufacturing of advanced materials where solvent residue limits are strict. The high assay value ensures minimal contamination in final products. Technical support is available to assist customers in optimizing formulation parameters for specific application requirements.
Quality Specifications
Quality assurance is central to our manufacturing philosophy. Each production lot undergoes comprehensive analysis using gas chromatography and Karl Fischer titration. The following table outlines typical specification parameters and test results conforming to our factory standards.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | Colorless and Clear liquid | Colorless and Clear liquid |
| Water Content | ≤300ppm | 240ppm |
| Acidity base on acetic acid | ≤200ppm | 80ppm |
| Basicity base on Dimethylamine | ≤100ppm | 28ppm |
| PH (25°C, 20% aqueous solution) | 4.0~8.0 | 6.8 |
| Relative Density (20°C) | 0.938~0.942 g/ml | 0.94 g/ml |
| Assay | ≥99.5% | 99.83% |
| Conclusion | Conforms to Factory Standard | |
Safety and Storage
Proper handling and storage are essential to maintain product integrity and ensure workplace safety. N,N-Dimethylacetamide is combustible and should be stored away from open flames and high-temperature sources. Warehouses must be well-ventilated to prevent vapor accumulation. It is incompatible with strong oxidizing agents and should be stored separately to avoid hazardous reactions.
Packaging is designed to prevent leakage and contamination during transport. We recommend using complete packaging with light loading and unloading procedures. Personal protective equipment should be worn during handling to minimize exposure. Comprehensive safety data sheets are provided with every shipment to guide safe usage and emergency response procedures. Our logistics network ensures timely delivery while adhering to all regulatory transportation requirements.
