Intermediates

N,N-Disuccinimidyl carbonate

  • CAS No.74124-79-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity N,N-Disuccinimidyl carbonate coupling reagent for peptide synthesis and bioconjugation. Available in bulk with comprehensive COA.

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Product Technical Details

Product Overview

N,N-Disuccinimidyl carbonate, commonly known as DSC, is a highly efficient carbonylating agent widely utilized in organic synthesis and bioconjugation applications. As a critical chemical intermediate, it serves as an active carbonate ester that facilitates the introduction of carbonyl groups into various molecular structures. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for sensitive pharmaceutical research and industrial scale production. This reagent is particularly valued for its stability and reactivity profile, allowing for precise control during complex synthetic routes.

Key Features and Advantages

Our premium grade N,N-Disuccinimidyl carbonate is produced under strict quality control standards to guarantee consistency across batches. The product offers several distinct advantages for chemists and process engineers looking for reliable coupling agents.

  • High Reactivity: Efficiently activates carboxyl groups for amide bond formation.
  • Superior Purity: Delivered with HPLC purity exceeding 99.0 percent to minimize side reactions.
  • Excellent Stability: Maintains integrity under proper storage conditions for extended periods.
  • Versatile Solubility: Soluble in common organic solvents such as DMF and DMSO for flexible application.
  • Low Moisture Content: Rigorously dried to prevent hydrolysis during storage and usage.

Technical Specifications

We adhere to rigorous analytical standards to ensure every drum meets the specified criteria. Below is the detailed certificate of analysis summary for our standard production batch.

Items of AnalysisStandard of AnalysisTest Results
AppearanceOff-white or White crystalline powderConform
Purity (HPLC)Greater than or equal to 99.0 percent99.4 percent
Melting point200.0 to 222.0 degrees Celsius220.4 to 221.2 degrees Celsius
Loss on dryingLess than or equal to 0.5 percent0.10 percent
ConclusionConforms to Factory Standard

Industrial Applications

This chemical intermediate plays a pivotal role in the synthesis of peptides, proteins, and antibody-drug conjugates. It is frequently employed to protect amine functionalities or to link biomolecules with functional tags. In the pharmaceutical sector, it supports the development of novel therapeutics by enabling precise molecular modifications. Additionally, it is used in polymer chemistry to introduce reactive sites onto polymer chains. The reliability of our supply chain ensures that research and production timelines are met without compromise.

Storage and Handling

To maintain optimal quality, N,N-Disuccinimidyl carbonate should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent exposure to humidity, which can lead to degradation. We recommend handling this material in a well-ventilated fume hood while wearing appropriate personal protective equipment. For large scale operations, our packaging options include 25 kg drums, with custom packaging available upon request to suit specific logistical requirements.