Intermediates

N-Phenyltrifluoromethanesulfonimide

  • CAS No.37595-74-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity N-Phenyltrifluoromethanesulfonimide serves as a premier trifluoromethanesulfonylation reagent for complex organic synthesis. It is essential for producing pharmaceutical and agrochemical intermediates with precision.

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Product Technical Details

Product Overview

N-Phenyltrifluoromethanesulfonimide, frequently recognized in the industry as Phenyl Triflimide, stands as a critical reagent within the realm of advanced organic chemistry. This specialized chemical compound is engineered to facilitate efficient trifluoromethanesulfonylation reactions, making it indispensable for researchers and manufacturers focused on high-performance molecular synthesis. Our facility produces this material under strict quality control protocols to ensure consistent batch-to-batch reliability for demanding industrial applications.

As a potent electrophilic trifluoromethanesulfonylating agent, this product enables the selective modification of various functional groups. Its robust chemical structure provides stability during storage while maintaining high reactivity under controlled reaction conditions. This balance makes it a preferred choice for synthesizing complex intermediates used in the development of novel pharmaceutical compounds, agrochemical solutions, and specialized materials.

Key Specifications

ParameterSpecification
Product NameN-Phenyltrifluoromethanesulfonimide
CAS Number37595-74-7
Molecular FormulaC8H5F6NO4S2
Molecular Weight357.25 g/mol
AppearanceWhite to off-white crystalline powder
Assay≥98.0%
Melting Point100-102 °C
Boiling Point305.3 °C at 760 mmHg
Density1.766 g/cm3
Refractive Index1.488

Industrial Applications

The primary utility of N-Phenyltrifluoromethanesulfonimide lies in its capability to introduce trifluoromethanesulfonyl groups into organic molecules. This transformation is vital for altering the physicochemical properties of target compounds, such as enhancing metabolic stability or modifying solubility profiles. It is commonly employed for the selective trifluoromethanesulfonylation of phenols, primary amines, and enols, serving as a foundational step in multi-step synthesis routes.

In the pharmaceutical sector, this reagent supports the creation of diverse drug candidates by enabling precise functional group manipulation. Additionally, it finds significant application in agrochemical synthesis, where fluorinated structures often confer improved biological activity and environmental persistence. Researchers also utilize this compound in the modification of sugars and proteins, expanding its utility into biochemical research and material science domains.

Quality Assurance And Storage

We prioritize product integrity through comprehensive quality assurance measures. Each production batch undergoes rigorous analytical testing to verify purity levels and confirm the absence of critical impurities such as N-Phenyltrifluoromethanesulphonamide and Aniline. Customers receive a detailed Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with international standards.

To maintain optimal quality, proper storage conditions are essential. The material should be kept in a cool, dry, and well-ventilated environment. Containers must remain tightly closed to prevent moisture absorption or contamination. When handled according to safety guidelines, this product presents minimal transport hazards, facilitating secure global logistics for our international clientele.