N-(tert-Butoxycarbonyl)sulfamide
- CAS No.148017-28-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-(tert-Butoxycarbonyl)sulfamide (CAS 148017-28-1) designed for pharmaceutical synthesis. Ideal intermediate for Doripenem production with ≥98.0% assay guarantee.
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Product Overview
N-(tert-Butoxycarbonyl)sulfamide, identified by CAS number 148017-28-1, represents a critical building block in the synthesis of advanced pharmaceutical compounds. This specialized chemical intermediate is engineered to meet the rigorous demands of modern medicinal chemistry, particularly in the production of carbapenem antibiotics. Our manufacturing process ensures consistent quality and high purity levels, making it a reliable choice for research and development teams as well as large-scale production facilities.
As a protected sulfamide derivative, this compound plays a pivotal role in introducing specific functional groups during complex organic synthesis. The tert-butoxycarbonyl (Boc) protecting group offers excellent stability under various reaction conditions while allowing for selective deprotection when required. This characteristic is essential for maintaining the integrity of sensitive molecular structures during multi-step synthesis pathways.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | N-(tert-Butoxycarbonyl)sulfamide |
| CAS Number | 148017-28-1 |
| Molecular Formula | C5H12N2O4S |
| Molecular Weight | 196.225 g/mol |
| Appearance | White to light yellow crystal powder |
| Assay (Purity) | ≥98.0% |
| Density | 1.3±0.1 g/cm3 |
| Packaging | 25 kg/drum or customized |
Industrial Applications
The primary application of N-(tert-Butoxycarbonyl)sulfamide lies in the pharmaceutical sector, specifically serving as a key intermediate in the synthesis of Doripenem. Doripenem is a broad-spectrum carbapenem antibiotic used to treat severe bacterial infections. The precision required in producing such active pharmaceutical ingredients demands intermediates of the highest quality to ensure final product safety and efficacy.
Beyond its specific use in antibiotic synthesis, this compound is valuable in general organic synthesis where sulfamide motifs are required. Researchers utilize this building block to explore new chemical entities and develop novel therapeutic agents. The stability and reactivity profile of this molecule make it suitable for various coupling reactions and functional group transformations.
Quality Assurance and Storage
We adhere to strict quality control protocols to guarantee that every batch of N-(tert-Butoxycarbonyl)sulfamide meets or exceeds industry standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA), detailing test results for purity, identity, and physical properties. Our laboratory employs advanced analytical techniques, including HPLC and NMR, to verify chemical structure and composition.
Proper storage is essential to maintain the stability of this chemical intermediate. It should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent degradation or contamination. We recommend following standard laboratory safety procedures when handling this material, including the use of appropriate personal protective equipment.
Supply and Logistics
As a global manufacturer, we are committed to providing reliable supply chains for our international clientele. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requirements based on specific customer needs. Our logistics network ensures timely delivery to major pharmaceutical hubs worldwide, supporting continuous production schedules and research timelines.
