Intermediates

N-Trimethylsilylimidazole

  • CAS No.18156-74-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade N-Trimethylsilylimidazole designed for efficient silylation and pharmaceutical intermediate synthesis with high stability.

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Product Technical Details

Product Overview

N-Trimethylsilylimidazole is a highly versatile silylating agent widely utilized in modern organic synthesis and pharmaceutical manufacturing. As a critical chemical intermediate, this compound facilitates the protection of hydroxyl and amino groups during complex multi-step synthesis routes. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for researchers and industrial chemists who require consistent performance and reliability in their reactions. The compound is characterized by its high reactivity and stability, which streamlines the protection and deprotection processes essential for producing advanced organic molecules.

Produced under strict quality control standards, this silylating reagent supports the development of novel therapeutic compounds and fine chemicals. Its efficiency in transferring the trimethylsilyl group reduces reaction times and improves overall yield in synthetic pathways. We are committed to supplying global markets with premium-grade chemical intermediates that meet rigorous international specifications.

Chemical Properties and Specifications

The physical and chemical characteristics of N-Trimethylsilylimidazole are optimized for industrial handling and laboratory use. The following table outlines the key technical parameters verified through our quality assurance protocols. Each batch is accompanied by a Certificate of Analysis to guarantee compliance with stated specifications.

ParameterSpecification
CAS Number18156-74-6
Molecular FormulaC6H12N2Si
Molecular Weight140.26 g/mol
AppearanceColorless transparent liquid
Purity (GC)≥99.0%
Density0.957 g/cm3
Boiling Point93-94°C
Melting Point-42°C
Flash Point6°C
Refractive Index1.475

Industrial Applications

This compound serves as a fundamental building block in the synthesis of pharmaceutical intermediates and specialty chemicals. Its primary function involves acting as a protective agent for sensitive functional groups, preventing unwanted side reactions during synthesis. By temporarily masking reactive sites, chemists can achieve higher selectivity and precision in constructing complex molecular architectures.

  • Efficient silylation of alcohols and amines in organic synthesis.
  • Protection group strategy for multi-step pharmaceutical manufacturing.
  • Enhancement of reaction yields in fine chemical production.
  • Compatible with various solvent systems for flexible process design.

Our clients utilize this reagent to develop advanced materials and therapeutic candidates. The high purity ensures minimal impurity carryover, which is crucial for downstream processing and regulatory compliance in regulated industries.

Storage and Handling

To maintain the integrity and performance of N-Trimethylsilylimidazole, proper storage conditions are essential. The product should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must be tightly sealed to prevent hydrolysis, as silylating agents are sensitive to atmospheric humidity. Safety protocols recommend using appropriate personal protective equipment during handling to avoid skin contact or inhalation of vapors.

We offer flexible packaging options, including standard drums and customized solutions based on customer requirements. Global shipping is available with full documentation support. For technical inquiries or bulk pricing requests, our expert team is ready to assist with comprehensive manufacturing process details and quality data.