O-Methyl-L-threonine
- CAS No.4144-02-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity O-Methyl-L-threonine (CAS 4144-02-9) designed for pharmaceutical intermediate synthesis. Available in bulk with strict quality control.
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Product Overview
O-Methyl-L-threonine is a specialized amino acid derivative characterized by the methylation of the hydroxyl group on the side chain of L-threonine. This structural modification enhances its stability and lipophilicity, making it a valuable building block in complex organic synthesis and pharmaceutical development. As a critical intermediate, it plays a pivotal role in the construction of peptide chains and the development of novel therapeutic agents. Our facility produces this compound under stringent quality management systems to ensure consistency and reliability for industrial-scale applications.
The compound is recognized for its high optical purity, which is essential for maintaining the stereochemical integrity of downstream pharmaceutical products. We understand that even minor impurities can affect the efficacy and safety of final drug substances. Therefore, our manufacturing process focuses on maximizing yield while minimizing by-products through advanced purification techniques.
Technical Specifications
We adhere to rigorous testing protocols to guarantee that every batch meets or exceeds industry standards. The following table outlines the key physical and chemical parameters for our standard grade O-Methyl-L-threonine.
| Parameter | Specification |
|---|---|
| CAS Number | 4144-02-9 |
| Molecular Formula | C5H11NO3 |
| Molecular Weight | 133.15 g/mol |
| Appearance | White Powder |
| Purity | ≥99.0% |
| Loss on Drying | ≤0.5% |
| Melting Point | 210-222°C |
| Storage Condition | 2-8°C |
Industrial Applications
This amino acid derivative is primarily utilized in the pharmaceutical industry as a key intermediate for the synthesis of bioactive peptides and small molecule drugs. Its unique chemical structure allows for selective protection and deprotection strategies during multi-step synthesis routes. Researchers and process chemists value O-Methyl-L-threonine for its compatibility with various coupling reagents and its stability under standard reaction conditions.
Beyond pharmaceuticals, this compound finds applications in biochemical research where modified amino acids are required to study protein structure and function. The methyl ether group provides resistance against certain enzymatic degradations, making it useful in the design of peptidomimetics with improved metabolic stability. Our clients rely on our supply chain to support their R&D initiatives and commercial production needs.
Quality Assurance and Packaging
Quality is the cornerstone of our operation. Each production batch undergoes comprehensive analysis using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a Certificate of Analysis (COA) with every shipment, detailing the test results against our specifications. This transparency ensures that our partners can integrate our materials into their processes with confidence.
Standard packaging consists of 25 kg drums, which are designed to protect the product from moisture and light during transit. However, we offer flexible packaging solutions to accommodate specific customer requirements, including smaller quantities for laboratory use. Proper storage is essential to maintain product integrity. We recommend storing the material in a cool, dry place at temperatures between 2-8°C, keeping the container tightly closed to prevent absorption of atmospheric moisture.
Why Choose Our Supply
As a global manufacturer with decades of experience in fine chemicals, we offer competitive bulk pricing without compromising on quality. Our logistics network ensures timely delivery to major markets worldwide. We are committed to supporting our clients with technical documentation and responsive customer service. Whether you are scaling up a synthesis route or sourcing materials for long-term production, our O-Methyl-L-threonine provides the reliability and performance your projects demand.
