(2S,3aR,7aS)-Octahydroindole-2-carboxylic Acid
- CAS No.145438-94-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2S,3aR,7aS)-Octahydroindole-2-carboxylic acid (CAS 145438-94-4) for pharmaceutical synthesis. Reliable supply for ACE inhibitor intermediates.
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Product Overview
(2S,3aR,7aS)-Octahydroindole-2-carboxylic Acid is a specialized chiral chemical intermediate widely utilized in the pharmaceutical industry. This compound serves as a critical building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly within the cardiovascular therapeutic sector. Our manufacturing process ensures high stereochemical purity, which is essential for maintaining the efficacy and safety profiles of downstream drug products.
As a dedicated chemical supplier, we understand the stringent requirements of modern drug development. This octahydroindole derivative is produced under strict quality control protocols to meet international standards. The specific stereochemistry (2S,3aR,7aS) is meticulously preserved during synthesis to ensure compatibility with complex multi-step reaction pathways required for advanced medicinal chemistry.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 145438-94-4 |
| Molecular Formula | C9H15NO2 |
| Molecular Weight | 169.221 g/mol |
| Appearance | White to off-white powder |
| Assay | ≥98.0% |
| Moisture Content | ≤0.5% |
| Melting Point | 307-309°C (dec.) |
| Density | 1.1±0.1 g/cm3 |
Industrial Applications
This chemical intermediate is primarily employed in the production of ACE inhibitors, a class of medications used to manage cardiovascular conditions. Specifically, it acts as a key precursor in the manufacturing processes of Trandolapril and Perindopril. The high purity level of our product minimizes impurity carry-over, facilitating smoother downstream processing and higher yields in final API synthesis.
Beyond cardiovascular applications, this octahydroindole structure offers versatility for organic synthesis research. It serves as a valuable scaffold for developing new therapeutic agents requiring rigid cyclic amino acid structures. Our clients utilize this material for process development, scale-up studies, and commercial production runs.
Quality Assurance and Packaging
We prioritize quality and safety in every shipment. Each batch of (2S,3aR,7aS)-Octahydroindole-2-carboxylic Acid undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to confirm identity and purity. A Certificate of Analysis (COA) is provided with every order to ensure full traceability and compliance with your internal quality standards.
- Standard packaging includes 25 kg drums suitable for industrial use.
- Custom packaging solutions are available upon request to meet specific logistics needs.
- Products are stored in cool, ventilated facilities to maintain stability during warehousing.
- Global shipping capabilities ensure timely delivery to manufacturing sites worldwide.
Our commitment to excellence extends beyond the product itself. We offer technical support to assist with integration into your synthesis routes. By choosing our facility as your partner, you gain access to a reliable supply chain backed by years of experience in fine chemical manufacturing. Contact our sales team today to discuss your requirements and request a quote for bulk quantities.
