(2S,3aS,7aS)-Octahydroindole-2-carboxylic acid
- CAS No.80875-98-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a critical chiral intermediate for ACE inhibitor production. We provide reliable bulk supply with full documentation.
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Product Overview
(2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a highly specialized chiral building block essential for the pharmaceutical industry. This compound serves as a key structural component in the synthesis of advanced antihypertensive medications. Our manufacturing process ensures exceptional stereochemical purity, which is vital for the efficacy and safety of the final therapeutic products. We maintain strict control over every production batch to meet the rigorous demands of global pharmaceutical supply chains.
As a leading supplier in the fine chemicals sector, we understand the critical nature of chiral intermediates. Our facility is equipped with state-of-the-art synthesis and purification technologies. This allows us to deliver consistent quality while optimizing production efficiency. The compound is characterized by its stable crystalline structure and high reactivity in subsequent coupling reactions, making it an ideal choice for complex organic synthesis workflows.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 80875-98-5 |
| Molecular Formula | C9H15NO2 |
| Molecular Weight | 169.22 g/mol |
| Appearance | Off-white to light yellow crystalline powder |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 252.0-260.0°C |
| Specific Rotation | -44.0° to -50.0° |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.5% |
Industrial Applications
This chemical intermediate is primarily utilized in the manufacturing of angiotensin-converting enzyme (ACE) inhibitors. It plays a pivotal role in constructing the core indole scaffold required for these cardiovascular medications. Beyond its primary use, the compound is valuable in research and development settings focused on novel peptidomimetics and heterocyclic chemistry. Its well-defined stereochemistry allows chemists to predict reaction outcomes with high precision.
Our clients leverage this material for scale-up processes ranging from pilot plant operations to full commercial production. The versatility of this building block supports various synthetic routes, providing flexibility in process chemistry. We work closely with R&D teams to ensure the material integrates seamlessly into existing manufacturing protocols.
Quality Assurance and Logistics
- Comprehensive Quality Control: Every batch undergoes rigorous testing using HPLC, NMR, and polarimetry to confirm identity and purity.
- Regulatory Support: We provide complete documentation packages including Certificates of Analysis (COA), Method of Analysis (MOA), and stability data.
- Secure Packaging: Products are sealed in moisture-proof containers within steel drums to prevent degradation during transit.
- Global Distribution: Our logistics network ensures timely delivery to major pharmaceutical hubs across Asia, Europe, and the Americas.
- Custom Synthesis: We offer tailored production services to meet specific purity requirements or alternative packaging needs.
Storage recommendations include keeping the material in a cool, ventilated environment away from direct sunlight and moisture. Proper handling ensures the longevity and performance of the chemical throughout its shelf life. Our technical support team is available to assist with any inquiries regarding application methods or safety data.
