Intermediates

(Oxydi-2,1-phenylene)bis(diphenylphosphine)

  • CAS No.166330-10-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity (Oxydi-2,1-phenylene)bis(diphenylphosphine) CAS 166330-10-5 designed for advanced pharmaceutical intermediate synthesis and catalytic applications.

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Product Technical Details

Product Overview

(Oxydi-2,1-phenylene)bis(diphenylphosphine) is a high-performance organophosphorus compound widely recognized for its exceptional stability and efficacy in complex organic synthesis. As a critical bidentate ligand, this chemical plays a pivotal role in facilitating transition metal-catalyzed reactions, particularly within the pharmaceutical and fine chemical industries. Our manufacturing process ensures superior consistency, making it an ideal choice for researchers and industrial producers seeking reliable performance in catalytic cycles.

This compound is characterized by its robust molecular structure, which enhances its ability to coordinate with metal centers such as palladium and nickel. This coordination is essential for driving cross-coupling reactions, hydrogenation processes, and other transformative synthetic steps required in the production of advanced pharmaceutical intermediates. The high purity levels we maintain guarantee minimal side reactions, leading to improved yields and reduced downstream purification costs.

Key Specifications

ParameterSpecification
CAS Number166330-10-5
Molecular FormulaC36H28OP2
Molecular Weight538.55 g/mol
AppearanceWhite Solid Powder
Purity (HPLC)≥99.0%
Melting Point184-187 °C
Packing25 kg/drum or customized

Industrial Applications

The primary application of (Oxydi-2,1-phenylene)bis(diphenylphosphine) lies in the synthesis of pharmaceutical intermediates. Its unique steric and electronic properties make it indispensable for modern catalytic methodologies. By optimizing reaction kinetics, this ligand supports the efficient construction of complex molecular architectures required in drug discovery and development.

  • Enhances catalytic activity in palladium-coupled reactions.
  • Improves selectivity in asymmetric synthesis protocols.
  • Suitable for large-scale industrial manufacturing processes.
  • Compatible with various solvent systems used in organic chemistry.

Quality Assurance and Storage

Quality is paramount in chemical manufacturing. Each batch of (Oxydi-2,1-phenylene)bis(diphenylphosphine) undergoes rigorous testing using advanced analytical techniques including HPLC and NMR spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with every shipment to verify compliance with international standards. Our facility adheres to strict quality management systems to ensure product integrity from synthesis to delivery.

For optimal preservation, this product should be stored in a cool, dry environment away from direct sunlight and moisture. Containers must remain tightly sealed to prevent oxidation or contamination. When handled according to standard safety protocols, this material offers excellent shelf stability, ensuring that its chemical properties remain intact over extended storage periods. We offer flexible packaging solutions to meet specific logistical requirements, including bulk drum shipments and customized containment options.