p-Fluorotoluene
- CAS No.352-32-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity p-Fluorotoluene (CAS 352-32-9), a key aromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.
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Product Overview
p-Fluorotoluene (CAS 352-32-9) is a high-value aromatic fluorinated compound widely employed as a versatile building block in fine chemical synthesis. With its well-defined reactivity profile and excellent stability under standard handling conditions, it serves as a critical precursor in the production of active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials. Our product meets stringent quality benchmarks, ensuring consistent performance in complex multi-step syntheses.
Specifications
| Molecular Formula | C₇H₇F |
|---|---|
| Molecular Weight | 110.129 g/mol |
| Appearance | Colorless transparent liquid |
| Assay | ≥98.0% |
| Boiling Point | 117.0 ± 9.0 °C at 760 mmHg |
| Melting Point | −56 °C (lit.) |
| Density | 1.0 ± 0.1 g/cm³ |
| Flash Point | 17.2 ± 0.0 °C |
| Vapour Pressure | 21.1 ± 0.2 mmHg at 25°C |
| Refractive Index | 1.477 |
Industrial Applications
As a foundational intermediate in organic chemistry, p-Fluorotoluene is extensively utilized in:
- The synthesis of fluorinated pharmaceuticals requiring para-substituted aromatic scaffolds
- Manufacturing of herbicides, fungicides, and other agrochemical actives
- Preparation of liquid crystals and electronic materials
- Serving as a starting material for further functionalization via electrophilic substitution or metal-catalyzed cross-coupling reactions
Its electron-donating methyl group and electron-withdrawing fluorine atom create a unique electronic balance that enables selective transformations, making it indispensable in modern synthetic routes.
Handling and Storage
Store in a cool, well-ventilated area away from heat, sparks, and open flames. Keep container tightly closed and protected from moisture. Use appropriate personal protective equipment during handling. Packaging is typically provided in 200 kg drums, with custom options available upon request to meet specific logistical or regulatory requirements.
