Intermediates

p-Toluenesulfonic Acid

  • CAS No.104-15-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity p-Toluenesulfonic Acid (CAS 104-15-4) supplied for organic synthesis and pharmaceutical intermediate production.

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Product Technical Details

Product Overview

p-Toluenesulfonic Acid, frequently abbreviated as PTSA or TsOH, stands as a cornerstone reagent in modern organic synthesis and industrial chemistry. As a strong organic acid, it offers exceptional solubility in organic solvents while maintaining high catalytic activity. Our manufacturing facility produces this compound with rigorous quality control standards to ensure consistency across large-scale production batches. This product is specifically engineered for professionals requiring reliable performance in esterification, dehydration, and condensation reactions.

We understand that purity is critical when selecting intermediates for downstream pharmaceutical or agrochemical synthesis. Therefore, our production process emphasizes the removal of moisture and inorganic impurities. The resulting material presents as a free-flowing white powder, facilitating easy handling and precise dosing in automated reactor systems. By choosing our supply chain, partners gain access to a stable source of high-grade chemical intermediates supported by comprehensive documentation.

Technical Specifications

ParameterSpecification
Chemical Namep-Toluenesulfonic Acid
CAS Number104-15-4
Molecular FormulaC7H8O3S
Molecular Weight172.202 g/mol
AppearanceWhite powder
Assay≥99.0%
Melting Point106~107℃
Boiling Point116 °C
Density1.3±0.1 g/cm3

Industrial Applications

The versatility of p-Toluenesulfonic Acid makes it indispensable across multiple chemical sectors. In the pharmaceutical industry, it serves as a vital catalyst for synthesizing active pharmaceutical ingredients (APIs) and complex intermediates. Its role extends into agrochemical production, where it facilitates the creation of protective crop solutions. Additionally, polymer chemists utilize this acid for resin modification and curing processes.

  • Acts as a potent acid catalyst in esterification and transesterification reactions.
  • Utilized in the synthesis of pharmaceutical intermediates such as antibiotics.
  • Employed in agrochemical manufacturing for specific pesticide formulations.
  • Serves as a standard reference material in analytical chemistry laboratories.
  • Effective in dehydration reactions requiring non-oxidizing acidic conditions.

Storage and Handling

To maintain optimal quality, proper storage protocols must be observed. The product should be kept in a cool, ventilated environment away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent hygroscopic absorption, which could affect catalytic efficiency. We recommend using compatible personal protective equipment during handling to ensure safety compliance. Our packaging options include standard 25 kg drums, with flexibility to accommodate custom logistical requirements for global shipping.