Intermediates

Pentyl chloroformate

  • CAS No.638-41-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade Pentyl chloroformate designed for pharmaceutical intermediate synthesis, ensuring high purity and consistent quality for large-scale production.

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Product Technical Details

Product Overview

Pentyl chloroformate, also known chemically as Carbonochloridic acid pentyl ester, stands as a critical reagent in the realm of advanced organic synthesis. As a member of the chloroformate ester family, this compound is extensively utilized in the pharmaceutical and fine chemical industries for acylation reactions and the introduction of protecting groups. Our manufacturing process ensures that every batch meets rigorous international standards, providing a reliable foundation for complex molecular construction.

In the context of modern drug development, the purity and stability of starting materials are paramount. Pentyl chloroformate serves as a versatile building block, facilitating the synthesis of various active pharmaceutical ingredients (APIs). Specifically, it plays a significant role in the production chain of oncology therapeutics, acting as a key intermediate in the manufacturing of compounds such as Capecitabine. Our commitment to quality ensures that downstream synthesis proceeds with minimal impurities, enhancing overall yield and safety.

Technical Specifications

To support precise laboratory and industrial operations, we provide comprehensive physical and chemical data. The following parameters are verified through advanced analytical techniques including gas chromatography and spectroscopic analysis.

ParameterValue
CAS Number638-41-5
Molecular FormulaC6H11ClO2
Molecular Weight150.603 g/mol
AppearanceColorless transparent liquid
Assay (Purity)≥99.0%
Density1.1±0.1 g/cm3
Boiling Point164.9±9.0 °C at 760 mmHg
Flash Point47.7±11.9 °C
Refractive Index1.426
Vapour Pressure1.9±0.3 mmHg at 25°C

Industrial Applications

The primary utility of Pentyl chloroformate lies in its reactivity with nucleophiles such as amines and alcohols. This characteristic makes it indispensable for creating carbamate derivatives and carbonate esters. In the pharmaceutical sector, it is employed to protect amino groups during multi-step synthesis, ensuring that reactions occur at specific sites without unwanted side effects.

  • Pharmaceutical Intermediate Synthesis: Essential for constructing complex drug molecules.
  • Organic Chemistry Research: Used in laboratories for developing new synthetic routes.
  • Fine Chemical Production: Serves as a precursor for specialized agrochemicals and materials.
  • Quality Control: High purity ensures consistent results in sensitive catalytic processes.

Quality Assurance and Packaging

We understand that consistency is the cornerstone of industrial chemistry. Each production lot undergoes strict quality control protocols, resulting in a Certificate of Analysis (COA) that accompanies every shipment. Our facility adheres to good manufacturing practices to minimize variability and ensure product integrity from synthesis to delivery.

Standard packaging includes 200 kg drums, designed to maintain stability during transit. However, we recognize that different clients have unique logistical requirements. Therefore, we offer flexible packaging solutions tailored to specific customer needs, ensuring safe handling and storage regardless of order volume.

Safety and Storage Guidelines

Pentyl chloroformate is a reactive chemical that requires careful handling. It is sensitive to moisture and may hydrolyze upon exposure to water, releasing hydrogen chloride gas. Consequently, storage conditions must be strictly controlled to preserve product quality and ensure personnel safety.

Stores should be kept in a cool, ventilated place away from direct sunlight and heat sources. Containers must remain tightly sealed when not in use. Personnel handling this material should utilize appropriate personal protective equipment (PPE), including chemical-resistant gloves and eye protection, to prevent skin contact and inhalation of vapors. In case of spills, neutralize with appropriate agents and ventilate the area immediately.