Phosphorus Tribromide
- CAS No.7789-60-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Phosphorus Tribromide (≥99.0%) is a key brominating reagent widely used in organic synthesis and pharmaceutical intermediate manufacturing.
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Product Overview
Phosphorus Tribromide (PBr₃), with CAS number 7789-60-8, is a versatile inorganic reagent extensively employed in the chemical and pharmaceutical industries as a potent brominating and reducing agent. Supplied as a colorless to light yellow fuming liquid, it meets stringent quality standards with a minimum purity of 99.0%, ensuring reliability in sensitive synthetic applications.
Specifications
| Molecular Formula | Br₃P |
|---|---|
| Molecular Weight | 270.69 g/mol |
| Density | 2.88 g/mL at 20 °C |
| Boiling Point | 175 °C |
| Melting Point | -40 °C |
| Flash Point | 172.9 °C |
| Refractive Index | 1.697 |
| Appearance | Colorless to light yellow liquid |
| Purity | ≥99.0% |
Industrial Applications
Phosphorus Tribromide serves as a critical intermediate in advanced organic synthesis. Its primary functions include:
- Converting alcohols to alkyl bromides with high efficiency and selectivity.
- Participating in the Hell-Volhard-Zelinsky reaction for α-bromination of carboxylic acids.
- Acting as a Lewis acid catalyst or bromine source in heterocyclic compound construction.
- Facilitating the preparation of other brominated building blocks for agrochemicals and active pharmaceutical ingredients (APIs).
Due to its reactivity with water and air moisture, strict handling protocols are required. It must be stored in a cool, dry, well-ventilated area, segregated from alkalis, oxidizing agents, organic materials, and flammable substances. Standard packaging is 25 kg per drum, with custom options available upon request to meet global regulatory and logistical requirements.
