Intermediates

Potassium 2-((Difluoromethyl)thio)acetate

  • CAS No.1797117-16-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Potassium 2-((Difluoromethyl)thio)acetate is a specialized fluorinated intermediate designed for advanced organic synthesis in agrochemical and pharmaceutical applications.

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Product Technical Details

Product Overview

Potassium 2-((Difluoromethyl)thio)acetate represents a sophisticated fluorinated building block essential for modern chemical synthesis. This compound features a unique difluoromethylthio group attached to an acetate backbone, stabilized as a potassium salt. The introduction of fluorine atoms into organic molecules is a critical strategy in contemporary medicinal chemistry and agrochemical design, often enhancing metabolic stability, lipophilicity, and bioavailability. Our manufacturing process ensures that this intermediate meets rigorous standards required for downstream synthesis of complex molecules.

As a key reagent, this substance facilitates the introduction of the SCF2H moiety into various organic frameworks. The potassium salt form offers improved handling characteristics and solubility profiles compared to its acidic counterparts, making it highly suitable for nucleophilic substitution reactions and other transformation processes used in research and industrial production scales.

Technical Specifications

Items of AnalysisStandard of AnalysisTest Results
AppearanceOff-white to yellow crystalline powderOff-white crystalline powder
Assay99.0% to 102.0%99.40%
Loss on dryingLess than or equal to 0.50%0.10%
Water (KF)Less than or equal to 0.50%0.10%
pH6 to 87.4
Total impurityLess than or equal to 2.00%0.30%
Potassium thioglycolateLess than or equal to 0.20%None
ConclusionConforms to Factory Standard

Industrial Applications

This fluorinated intermediate finds extensive utility across multiple high-value sectors. In the agrochemical industry, it serves as a precursor for developing novel pesticides and herbicides where fluorine substitution enhances environmental stability and efficacy. In pharmaceutical research, it is utilized in the synthesis of active pharmaceutical ingredients (APIs) where specific fluorine placement is required to modulate drug-receptor interactions. Additionally, material science researchers employ this compound in the development of specialized polymers and functional materials requiring precise chemical modification.

The versatility of the difluoromethylthio group allows chemists to explore new chemical spaces, enabling the creation of molecules with improved performance characteristics. Whether used in scale-up production or laboratory research, consistency in quality is paramount for achieving reproducible results in final product formulations.

Quality Assurance and Control

Our commitment to quality begins with raw material selection and extends through every stage of production. Each batch of Potassium 2-((Difluoromethyl)thio)acetate undergoes comprehensive analytical testing using advanced instrumentation including High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), and Karl Fischer titration. These tests verify identity, purity, and moisture content to ensure compliance with specified parameters.

We maintain strict documentation practices, providing a Certificate of Analysis (COA) with every shipment. Our quality management system adheres to international standards, ensuring traceability and consistency. Regular audits and process validations are conducted to maintain the highest levels of product integrity and safety for our global clientele.

Storage and Handling

To maintain optimal stability, this product should be stored in a cool, dry, and well-ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent hydration or contamination. Handling should be performed in accordance with standard laboratory safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles. Proper disposal methods should be followed in compliance with local environmental regulations.

We offer flexible packaging options to suit various production needs, ranging from laboratory-scale quantities to bulk industrial shipments. Our logistics network ensures timely delivery worldwide, supported by responsive customer service to address any technical inquiries or supply chain requirements.