Propargylaldehyde Diethyl Acetal
- CAS No.10160-87-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity organic synthesis intermediate featuring stable acetal protection and alkyne functionality for advanced chemical manufacturing.
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Product Overview
Propargylaldehyde Diethyl Acetal is a highly versatile organic building block extensively utilized in modern pharmaceutical and fine chemical synthesis. As a protected form of propargylaldehyde, this compound offers enhanced stability during storage and handling while retaining the reactive alkyne functionality required for complex molecular construction. Our facility produces this intermediate under strict quality control protocols to ensure consistent performance in downstream chemical reactions.
This chemical serves as a critical precursor in the development of advanced therapeutic agents and specialized materials. The diethyl acetal group provides robust protection against unwanted oxidation or polymerization, allowing chemists to perform selective transformations on other parts of the molecule before deprotecting the aldehyde functionality when needed. This strategic advantage makes it an indispensable tool for multi-step synthetic routes.
Chemical Properties and Specifications
Understanding the physical and chemical characteristics of Propargylaldehyde Diethyl Acetal is essential for safe and effective usage in industrial applications. The compound is characterized by its distinct molecular structure, which combines an alkyne group with an acetal protection moiety. Below are the key technical specifications verified through our internal quality assurance laboratory.
| Parameter | Specification |
|---|---|
| Chemical Name | Propargylaldehyde Diethyl Acetal |
| CAS Number | 10160-87-9 |
| Molecular Formula | C7H12O2 |
| Molecular Weight | 128.17 g/mol |
| Appearance | Light yellow or colorless transparent liquid |
| Purity (GC) | ≥97.0% |
| Density | 0.894 g/mL at 25 °C |
| Boiling Point | 138-139.5 °C |
| Refractive Index | n20/D 1.412 |
| Flash Point | 90 °F |
Industrial Applications
The primary utility of this compound lies in its role as a synthetic intermediate for pharmaceuticals, agrochemicals, and specialty polymers. The alkyne group enables participation in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloadditions, which are fundamental in modern drug discovery pipelines. Furthermore, the acetal functionality can be selectively hydrolyzed under acidic conditions to reveal the reactive aldehyde, facilitating subsequent condensation or reduction steps.
- Pharmaceutical Intermediate: Used in the synthesis of complex active pharmaceutical ingredients (APIs).
- Organic Synthesis: Acts as a building block for heterocyclic compounds and natural product analogs.
- Material Science: Employed in the development of functionalized polymers and conductive materials.
- Research and Development: Essential reagent for academic and industrial laboratories focusing on organic methodology.
Quality Assurance and Storage
We maintain a comprehensive quality management system to guarantee that every batch of Propargylaldehyde Diethyl Acetal meets or exceeds industry standards. Each production lot undergoes rigorous testing using gas chromatography and other analytical methods to verify purity and identity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance.
Proper storage is critical to maintaining the integrity of this chemical. It should be kept in a cool, dry place away from direct sunlight and sources of ignition. The recommended storage temperature is between 2-8ºC to prevent degradation over extended periods. Containers must be tightly sealed to avoid moisture absorption, which could lead to premature hydrolysis of the acetal group. Our packaging solutions are designed to ensure safe transport and long-term stability for global customers.
