Pyridine-3-Sulfonyl Chloride

Product Overview

Our organization specializes in the supply of premium-grade Pyridine-3-Sulfonyl Chloride, a vital heterocyclic building block extensively utilized in modern medicinal chemistry. Identified by CAS number 16133-25-8, this compound features a pyridine ring substituted with a sulfonyl chloride group at the third position. This specific structural arrangement imparts unique reactivity profiles, making it an indispensable reagent for introducing the pyridine-3-sulfonyl moiety into complex organic molecules. Our manufacturing processes adhere to strict international quality standards, ensuring consistent batch-to-batch reliability for large-scale industrial applications.

Technical Specifications

We maintain rigorous quality control protocols to guarantee the chemical integrity of every shipment. The following table outlines the key physical and chemical properties associated with our standard production grade. Please note that specific parameters may vary slightly based on custom purification requirements.

Industrial Applications

The primary application of Pyridine-3-Sulfonyl Chloride lies in the synthesis of advanced pharmaceutical active ingredients. It serves as a key intermediate in the production of Vonoprazan fumarate, a potent potassium-competitive acid blocker used in the treatment of acid-related disorders. Beyond this specific pathway, the compound acts as a versatile sulfonylating agent in the construction of sulfonamides and sulfonates. Its compatibility with various nucleophiles allows chemists to develop diverse libraries of compounds for drug discovery programs. The high purity levels we provide minimize side reactions, thereby improving overall yield and reducing downstream purification costs for our clients.

Quality Assurance and Storage

Quality is paramount in our operations. Each batch undergoes comprehensive analysis using high-performance liquid chromatography (HPLC) and gas chromatography (GC) to verify purity and identify impurities. A Certificate of Analysis (COA) is provided with every order. Regarding storage, this chemical is moisture-sensitive and should be kept in a tightly closed container. It must be stored in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents, bases, and water. Proper handling procedures, including the use of personal protective equipment, are recommended to ensure safety during transfer and usage. We offer flexible packaging options, including 25kg cardboard drums, tailored to meet specific logistical requirements.