Pyrrolidone Hydrotribromide
- CAS No.22580-55-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Pyrrolidone Hydrotribromide (CAS 22580-55-8) designed for pharmaceutical synthesis, specifically as a key intermediate for Silodosin production.
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Product Overview
Pyrrolidone Hydrotribromide is a specialized chemical reagent widely recognized in the pharmaceutical industry for its efficacy in controlled bromination reactions. As a stable complex formed between pyrrolidin-2-one and bromine, this compound offers a significantly safer and more manageable alternative to handling elemental bromine directly in industrial settings. Our manufacturing process ensures high consistency and exceptional purity, making it an essential building block for complex organic synthesis pathways required in modern medicinal chemistry.
Designed for professional laboratory and large-scale industrial applications, this product meets stringent quality standards required for pharmaceutical intermediate production. The compound is particularly valued for its favorable solubility profile and predictable reaction kinetics, which facilitate efficient synthesis routes while minimizing unwanted side reactions and impurities. We prioritize supply chain stability to support continuous manufacturing operations.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 22580-55-8 |
| Molecular Formula | C4H7Br3NO |
| Molecular Weight | 324.82 g/mol |
| Appearance | Orange to dark red crystals |
| Assay | ≥97.0% |
| Melting Point | 87-91°C |
| Density | 1.047 g/cm3 |
| Boiling Point | 245°C at 760mmHg |
| Flash Point | 135.5°C |
Industrial Applications
The primary application of Pyrrolidone Hydrotribromide lies in the synthesis of active pharmaceutical ingredients (APIs). It serves as a critical intermediate in the production of Silodosin, a therapeutic agent used in urology for the treatment of benign prostatic hyperplasia. The high purity level of our product ensures that downstream purification processes are optimized, reducing overall production costs and time-to-market for finished drugs.
- Key intermediate for alpha-blocker synthesis pathways.
- Effective brominating agent for selective organic transformations.
- Suitable for scale-up from pilot plant to commercial manufacturing.
- Compatible with various solvent systems used in medicinal chemistry.
- Supports regulatory compliance for API starting materials.
Quality Assurance and Storage
We adhere to rigorous quality control protocols to guarantee the integrity of every batch produced. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying compliance with specified parameters including assay, melting point, and physical appearance. Our quality assurance team utilizes advanced analytical methods such as HPLC and titration to ensure consistency across all production lots.
To maintain chemical stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper handling procedures are recommended to ensure safety during industrial operations, including the use of appropriate personal protective equipment. Our packaging options include standard 25 kg drums, with flexibility to accommodate specific customer logistics requirements. As a global manufacturer, we support international shipping and provide comprehensive technical documentation to facilitate regulatory compliance in your region.
