(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
- CAS No.330156-50-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity chiral intermediate essential for pharmaceutical synthesis, specifically designed for kinase inhibitor production with strict quality control.
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Product Overview
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is a specialized chiral chemical intermediate widely utilized in the pharmaceutical industry. This compound serves as a critical building block in the synthesis of advanced therapeutic agents, particularly within the realm of oncology treatments. Its specific stereochemistry ensures high efficacy in downstream reactions, making it a preferred choice for manufacturers requiring precise molecular configurations.
Our facility produces this intermediate using state-of-the-art asymmetric synthesis techniques to guarantee exceptional enantiomeric excess. The presence of chloro and fluoro substituents on the phenyl ring enhances the chemical stability and reactivity required for complex coupling reactions. We maintain rigorous production standards to ensure consistency across all batches, supporting large-scale pharmaceutical manufacturing needs.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 330156-50-8 |
| Molecular Formula | C8H7Cl2FO |
| Molecular Weight | 209.045 g/mol |
| Purity | ≥98.0% |
| Appearance | Light yellow or yellow solid |
| Water Content | ≤0.50% |
| Melting Point | 41.0 to 45.0 °C |
| Boiling Point | 747.5±70.0 °C at 760 mmHg |
Industrial Applications
This chemical is primarily employed as a key intermediate in the manufacturing of kinase inhibitors. It plays a vital role in the synthesis pathway of specific anticancer medications, contributing to the formation of the active pharmaceutical ingredient. The high purity level ensures minimal impurity carryover, which is crucial for meeting regulatory standards in drug production.
Beyond oncology, this compound may be utilized in research and development for new medicinal chemistry projects requiring chiral benzylic alcohol structures. Its reactivity profile allows for versatile functionalization, enabling chemists to explore diverse molecular architectures during the drug discovery phase.
Quality Assurance
Quality is paramount in our manufacturing process. Each batch of (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, identity, and physical properties.
Our quality management system adheres to international standards, ensuring traceability and compliance. We perform regular audits of our supply chain and production facilities to maintain the highest levels of safety and product integrity. Customers can rely on our technical support team for assistance with specification customization or application guidance.
Packaging and Storage
To preserve stability and potency, the product is packaged in secure 25kg cardboard drums or according to specific customer requirements. Packaging materials are selected to prevent moisture ingress and protect against physical damage during transit. We offer flexible packaging solutions to accommodate various logistical needs.
Storage conditions are critical for maintaining product quality. We recommend storing the material in a cool, dry, and well-closed container. It should be kept away from moisture, strong light, and heat sources to prevent degradation. Proper handling procedures should be followed to ensure safety during unpacking and usage in laboratory or industrial settings.
