(R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol

Product Overview

(R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol is a specialized chiral building block designed for advanced pharmaceutical synthesis. This high-value intermediate plays a critical role in the production of novel neurokinin-1 (NK-1) receptor antagonists. Our manufacturing process ensures exceptional optical purity and chemical stability, meeting the rigorous demands of modern drug development pipelines.

As a key precursor in the synthesis of antiemetic agents, this compound undergoes strict quality control measures at every production stage. We utilize state-of-the-art chromatography and spectroscopy techniques to verify structural integrity and enantiomeric excess. This commitment to quality guarantees consistent performance in downstream reactions, reducing waste and optimizing yield for our global partners.

Technical Specifications

Industrial Applications

This compound serves as a vital intermediate in the manufacturing of Fosaprepitant and Aprepitant. These active pharmaceutical ingredients are widely recognized for their efficacy in preventing nausea and vomiting associated with chemotherapy. The specific stereochemistry of the (R)-enantiomer is crucial for biological activity, making our high optical rotation specification a key value proposition for API manufacturers.

Beyond direct API synthesis, this chemical is utilized in research and development settings for exploring new therapeutic pathways involving substance P antagonism. Its stability under various reaction conditions makes it a versatile reagent for organic synthesis laboratories focused on neurological therapeutics and supportive care medications.

Quality Assurance and Packaging

We understand that consistency is paramount in pharmaceutical supply chains. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing all critical quality attributes. Our packaging solutions are designed to maintain product integrity during transit and storage. Standard packaging includes 25kg drums, though we offer customized solutions to meet specific logistical requirements.

Proper storage is essential to maintain shelf life. We recommend keeping containers tightly closed in a cool, dry, and well-ventilated area. Our logistics team ensures compliance with international shipping regulations for chemical substances, providing documentation support for customs clearance worldwide. Partner with us for reliable supply, technical expertise, and a commitment to excellence in pharmaceutical intermediates.