(R)-(-)-1-Aminoindan
- CAS No.10277-74-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (R)-(-)-1-Aminoindan (CAS 10277-74-4) designed for pharmaceutical synthesis. Ideal intermediate for Rasagiline Mesylate production with guaranteed assay ≥98.0%.
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Product Overview
(R)-(-)-1-Aminoindan is a critical chiral building block extensively utilized in the pharmaceutical industry for the synthesis of advanced therapeutic agents. As a key intermediate, this compound plays a pivotal role in the manufacturing process of Rasagiline Mesylate, a well-known medication used in the management of Parkinson's disease. Our facility specializes in the production of high-quality optical isomers, ensuring that every batch meets stringent enantiomeric purity standards required for modern drug development.
We understand the complexities involved in chiral synthesis and offer a robust supply chain solution for research institutions and pharmaceutical manufacturers. By leveraging advanced catalytic resolution techniques, we deliver (R)-(-)-1-Aminoindan with consistent quality, supporting our partners in accelerating their drug discovery and production timelines. This product is manufactured under strict quality control protocols to ensure reliability and reproducibility in downstream chemical reactions.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | (R)-(-)-1-Aminoindan |
| CAS Number | 10277-74-4 |
| Molecular Formula | C9H11N |
| Molecular Weight | 133.190 |
| Appearance | Colorless to light yellow clear liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 225.0±19.0 °C at 760 mmHg |
| Melting Point | 15ºC |
| Flash Point | 94.4±0.0 °C |
Primary Applications
The primary application of (R)-(-)-1-Aminoindan lies in its function as a precursor for Rasagiline Mesylate synthesis. The stereochemistry of this molecule is crucial, as the biological activity of the final pharmaceutical product is highly dependent on the optical purity of the intermediate. Beyond this specific application, it serves as a versatile building block in organic synthesis for various neurological therapeutics and complex pharmaceutical APIs. Researchers utilize this compound to construct indanamine derivatives with specific biological profiles.
Quality Assurance and Advantages
- High Enantiomeric Excess: Ensures optimal yield in chiral drug synthesis.
- Strict Quality Control: Every batch is tested using HPLC and NMR spectroscopy.
- Scalable Production: Capable of meeting bulk demands for industrial manufacturing.
- Regulatory Compliance: Produced in facilities adhering to international safety and quality standards.
- Technical Support: Dedicated team available for synthesis route optimization and troubleshooting.
Storage and Packaging
To maintain stability and integrity, (R)-(-)-1-Aminoindan should be stored in a cool, ventilated place away from direct sunlight and moisture. We offer flexible packaging options to suit various logistical requirements, including standard 200 kg drums or custom packaging solutions based on customer specifications. Our logistics team ensures safe and timely global delivery, complete with necessary documentation such as Certificates of Analysis (COA) and safety data sheets. Partner with us for a reliable supply of premium chemical intermediates.
