(R)-(+)-1-Butyn-3-ol
- CAS No.42969-65-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (R)-(+)-1-Butyn-3-ol (CAS 42969-65-3) is a critical chiral intermediate for pharmaceutical synthesis, specifically Vorapaxar Sulfate. Available in bulk with strict quality control.
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Product Overview
Welcome to our comprehensive product profile for (R)-(+)-1-Butyn-3-ol, a specialized chiral intermediate essential for modern pharmaceutical manufacturing. This compound serves as a foundational building block in the synthesis of complex therapeutic agents, most notably acting as a key precursor in the production of Vorapaxar Sulfate. Our facility is dedicated to providing high-enantiomeric purity materials that meet the rigorous demands of global drug development pipelines.
In the realm of pharmaceutical chemistry, stereochemistry plays a pivotal role in determining the efficacy and safety of the final active pharmaceutical ingredient. (R)-(+)-1-Butyn-3-ol offers the specific spatial configuration required for downstream reactions, ensuring optimal yield and minimizing unwanted byproducts. We understand that consistency is paramount in medicinal chemistry, which is why every batch undergoes stringent analytical testing to verify structural integrity and purity levels.
Technical Specifications
To support your research and production needs, we maintain transparent and detailed specifications for all our chemical intermediates. The following table outlines the critical physical and chemical properties associated with this product line.
| Parameter | Value |
|---|---|
| CAS Number | 42969-65-3 |
| Molecular Formula | C4H6O |
| Molecular Weight | 70.090 g/mol |
| Appearance | Colorless transparent liquid |
| Assay (Purity) | ≥98.0% |
| Density | 0.89 g/cm3 |
| Boiling Point | 108-111 °C |
| Flash Point | 10 °C |
Industrial Applications
The primary application of (R)-(+)-1-Butyn-3-ol lies within the synthesis of antiplatelet medications. As a critical intermediate for Vorapaxar Sulfate, it contributes to the development of therapies aimed at reducing thrombotic cardiovascular events. Beyond this specific pathway, the compound is highly valued in organic synthesis for its reactive alkyne and hydroxyl functional groups. These features allow chemists to construct diverse molecular architectures efficiently.
Our clients utilize this material for various stages of drug discovery, including lead optimization and process scale-up. The high purity ensures that subsequent reaction steps proceed without interference from impurities, thereby saving time and resources during the manufacturing process. Whether used in laboratory-scale experimentation or industrial production, our product delivers reliable performance.
Quality Assurance and Logistics
We adhere to strict quality management systems to guarantee the safety and reliability of our chemical supplies. Each shipment is accompanied by a Certificate of Analysis (COA) that details the test results for identity, purity, and physical properties. Our packaging solutions are designed to maintain stability during transit, typically utilizing 25 kg drums or custom configurations based on client requirements.
Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances. As a global manufacturer, we offer competitive bulk pricing and efficient logistics support to ensure your supply chain remains uninterrupted. Partner with us for a dependable source of high-quality chiral intermediates that drive innovation in pharmaceutical science.
