(R)-1-(naphthalen-1-yl)ethanamine
- CAS No.3886-70-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (R)-1-(naphthalen-1-yl)ethanamine (CAS 3886-70-2) available for chiral synthesis and pharmaceutical intermediate applications. Global manufacturer supplying bulk quantities with COA.
Request Bulk PricingProduct Technical Details
Product Overview
(R)-1-(naphthalen-1-yl)ethanamine, also known as (R)-(+)-1-(1-Naphthyl)Ethylamine, is a critical chiral amine intermediate utilized extensively in advanced organic synthesis and pharmaceutical manufacturing. This compound features a naphthalene ring substituted with an ethylamine group at the 1-position, possessing a specific (R) stereochemistry that is essential for producing enantiomerically pure downstream products. Our facility specializes in the production of high-grade chiral intermediates, ensuring consistent quality and optical purity for demanding research and industrial applications.
As a key building block in medicinal chemistry, this amine serves as a precursor for various complex molecules, including calcimimetic agents and other therapeutic compounds. The strict control of stereochemistry during synthesis guarantees that the final pharmaceutical products meet rigorous regulatory standards. We employ state-of-the-art purification techniques to achieve assay levels exceeding 99.0 percent, minimizing impurities that could affect downstream reaction yields or product safety.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 3886-70-2 |
| Molecular Formula | C12H13N |
| Molecular Weight | 171.238 g/mol |
| Appearance | Yellow liquid |
| Assay | ≥99.0% |
| Water Content | ≤0.50% |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 289.9±0.0 °C at 760 mmHg |
| Flash Point | 144.3±11.5 °C |
| Refractive Index | 1.630 |
Industrial Applications
This chiral amine is primarily employed in the synthesis of pharmaceutical intermediates, including pathways leading to calcimimetic drugs used in the management of secondary hyperparathyroidism. Its high enantiomeric excess makes it suitable for asymmetric synthesis reactions, such as the preparation of beta-amino acids and the enantioselective addition of ketones to nitroolefins. Researchers and process chemists value this material for its reliability in creating chiral centers with high fidelity.
- Essential intermediate for complex pharmaceutical API synthesis.
- Used in chiral resolution and asymmetric catalysis.
- Applicable in the production of fine chemicals and specialty polymers.
- Supports research into new therapeutic agents requiring specific stereochemistry.
Quality Assurance and Packaging
Quality control is paramount in our manufacturing process. Each batch undergoes rigorous testing using HPLC, GC, and NMR spectroscopy to verify identity, purity, and optical rotation. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our packaging options are designed to maintain product integrity during transit, typically supplied in 25kg drums, though custom packaging solutions are available to meet specific client logistics requirements.
For storage, we recommend keeping the container tightly closed in a cool, dry, and well-ventilated area away from incompatible substances. Proper handling procedures should be followed to ensure safety, including the use of appropriate personal protective equipment. As a global manufacturer, we offer competitive bulk pricing and reliable supply chain management to support your production schedules efficiently.
