Intermediates

(R)-(-)-4-Phenyl-2-Oxazolidinone

  • CAS No.90319-52-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity chiral intermediate essential for Ezetimibe synthesis. Available in bulk with strict QC.

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Product Technical Details

Product Overview

(R)-(-)-4-Phenyl-2-Oxazolidinone is a highly specialized chiral building block utilized extensively in the pharmaceutical industry for asymmetric synthesis. This compound serves as a critical intermediate in the production of advanced therapeutic agents, most notably functioning as a key precursor in the manufacturing process of Ezetimibe. Our facility ensures that every batch meets rigorous international standards for chemical purity and stereochemical integrity, making it an ideal choice for large-scale pharmaceutical production.

As a leading global manufacturer, we understand the importance of consistency in chiral auxiliaries. The structural stability and high optical purity of this oxazolidinone derivative facilitate efficient reaction pathways, reducing waste and improving overall yield in downstream synthesis. We employ state-of-the-art analytical techniques to verify the configuration and purity of each lot, ensuring reliable performance in your specific application.

Key Specifications

Quality control is paramount in the supply of fine chemical intermediates. The following table outlines the critical physical and chemical parameters verified during our comprehensive quality assurance process. These specifications guarantee that the material performs consistently within expected tolerances for industrial synthesis.

ParameterSpecification
CAS Number90319-52-1
Molecular FormulaC9H9NO2
Molecular Weight163.173
AppearanceOff-white crystalline powder
Melting Point131-133 °C (lit.)
Assay (HPLC)≥99.0%
Chiral Assay (GC)≥99.5%
Total Impurities≤1.0%
Moisture Content≤0.5%

Industrial Applications

The primary application of (R)-(-)-4-Phenyl-2-Oxazolidinone lies in the synthesis of cholesterol absorption inhibitors. Its specific stereochemistry allows for the precise construction of complex molecular architectures required in modern cardiovascular medications. Beyond Ezetimibe, this intermediate is valuable in various organic synthesis routes where chiral induction is necessary to achieve the desired biological activity.

Chemists and process engineers value this compound for its reliability in multi-step synthesis. The high purity levels minimize the risk of side reactions, ensuring that the final active pharmaceutical ingredient meets regulatory requirements. Our technical team supports clients with detailed documentation regarding the synthesis route and compatibility with various reagents.

Quality Assurance and Logistics

We maintain a robust quality management system that covers every stage from raw material sourcing to final packaging. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing batch-specific test results. Our packaging options include 25 kg drums, with custom configurations available to suit specific logistical requirements.

Proper storage is essential to maintain product integrity. We recommend storing this material in a cool, ventilated place away from direct sunlight and moisture. Our global supply chain ensures timely delivery while maintaining strict compliance with international chemical safety standards. Partner with us for a reliable source of high-performance pharmaceutical intermediates.