(R)-(+)-Propylene Carbonate
- CAS No.16606-55-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade (R)-(+)-Propylene Carbonate intermediate designed for high-efficiency pharmaceutical synthesis and chiral building block applications.
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Product Overview
(R)-(+)-Propylene Carbonate is a high-value chiral building block extensively utilized in the fine chemical and pharmaceutical industries. As a key intermediate, this compound plays a critical role in the stereoselective synthesis of complex organic molecules. Our manufacturing process ensures exceptional optical purity and chemical stability, making it an ideal choice for researchers and industrial producers focused on advanced therapeutic development.
This cyclic carbonate derivative is characterized by its robust reactivity and compatibility with various synthetic routes. The chiral center provides the necessary stereochemical foundation for producing enantiomerically pure active pharmaceutical ingredients. We adhere to strict quality control protocols to guarantee consistency across every batch, supporting seamless scale-up from laboratory research to commercial production.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 16606-55-6 |
| Molecular Formula | C4H6O3 |
| Molecular Weight | 102.09 g/mol |
| Appearance | Colorless to light yellow liquid |
| Purity (HPLC) | ≥98% |
| Density | 1.189 g/mL at 20 °C |
| Boiling Point | 240 °C |
| Refractive Index | 1.422 |
| Flash Point | >230 °F |
| Total Impurities | ≤3.0% |
| Single Impurity | ≤1.0% |
Industrial Applications
The primary application of (R)-(+)-Propylene Carbonate lies in the synthesis of nucleotide analog intermediates. It is specifically valued in the production chain of antiviral medications, serving as a crucial precursor for compounds such as Tenofovir and its prodrug forms. The high optical purity of our product ensures that downstream reactions proceed with minimal racemization, thereby maximizing the yield and efficacy of the final pharmaceutical product.
Beyond antiviral therapeutics, this chemical serves as a versatile reagent in organic synthesis. It is employed in the preparation of various chiral auxiliaries and protecting groups. Our clients in the agrochemical and specialty material sectors also utilize this intermediate for developing novel compounds requiring precise stereochemical control. The versatility of this carbonate allows for diverse functionalization strategies, supporting innovation across multiple chemical domains.
Quality Assurance and Storage
Quality is paramount in our manufacturing operations. Each batch of (R)-(+)-Propylene Carbonate undergoes rigorous testing using high-performance liquid chromatography (HPLC) and other analytical methods to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our facilities operate under stringent safety and environmental standards to ensure product integrity and operational safety.
For optimal preservation, this product should be stored in a cool and dry environment within well-closed containers. It is essential to protect the material from moisture and strong light or heat sources to prevent degradation. Proper handling procedures should be followed to maintain the chemical's stability over time. We offer flexible packaging options, including 25kg cardboard drums, tailored to meet specific logistical requirements and customer preferences for bulk supply.
