Rhodanine-3-acetic Acid
- CAS No.5718-83-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Rhodanine-3-acetic Acid (CAS 5718-83-2) designed for pharmaceutical synthesis. Ideal intermediate for Epalrestat production with strict quality control.
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Product Overview
Rhodanine-3-acetic Acid represents a critical pharmaceutical intermediate characterized by its distinct thiazolidinone core structure. This compound serves as an essential building block in the synthesis of advanced therapeutic agents, specifically functioning as a key precursor in the manufacturing of Epalrestat. Our production facility adheres to stringent quality management systems to ensure that every batch meets the rigorous demands of modern medicinal chemistry. The chemical stability and reactivity profile of this molecule make it indispensable for researchers and industrial manufacturers focusing on aldose reductase inhibitors and related neurological therapeutics.
As a dedicated global manufacturer, we understand the importance of consistency in supply chain logistics. Our Rhodanine-3-acetic Acid is synthesized using optimized routes that maximize yield while minimizing impurity profiles. This commitment to excellence ensures that downstream processing remains efficient and cost-effective for our partners. Whether utilized in laboratory-scale research or large-scale commercial production, our material provides the reliability required for regulatory submission and final drug product approval. We prioritize transparency and technical support throughout the procurement process.
Technical Specifications
The following table outlines the critical physical and chemical parameters verified through our quality control laboratory. Each parameter is tested using validated analytical methods to guarantee compliance with international pharmacopoeia standards where applicable. Our data reflects typical values obtained from recent production batches, ensuring customers receive material that matches their specific formulation requirements.
| Parameter | Specification |
|---|---|
| Appearance | Yellow to Light Yellow Crystalline Powder |
| CAS Number | 5718-83-2 |
| Molecular Formula | C5H5NO3S2 |
| Molecular Weight | 191.23 g/mol |
| Assay (HPLC) | ≥ 98.0% |
| Melting Point | 146-149 °C |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Industrial Applications
The primary application of Rhodanine-3-acetic Acid lies within the pharmaceutical sector, specifically as an intermediate for Epalrestat. Epalrestat is widely recognized for its utility in managing diabetic neuropathy, making the quality of its precursors paramount. Beyond this specific use, the thiazolidine scaffold offers versatility for medicinal chemists exploring new chemical entities targeting metabolic disorders. The carboxylic acid functionality allows for various derivatization reactions, facilitating amide bond formation or esterification during complex synthesis routes.
- Key intermediate for Aldose Reductase Inhibitors.
- Utilized in the development of neurological therapeutics.
- Suitable for custom synthesis projects requiring thiazolidine cores.
- Supports scale-up from gram to multi-kilogram quantities.
Quality Assurance and Storage
We maintain a comprehensive quality assurance protocol that includes raw material inspection, in-process control, and final product verification. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for the batch received. To maintain stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper storage ensures that the physical characteristics and chemical potency remain intact throughout the shelf life. Our packaging options include 25 kg drums, with flexibility to accommodate specific customer requirements for bulk shipping or specialized containment. We are committed to delivering safe, compliant, and high-performance chemical solutions to our global clientele.
