Intermediates

(R,R)-2-Amino-1-(4-Nitrophenyl)Propane-1,3-Diol

  • CAS No.716-61-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity (R,R)-2-Amino-1-(4-Nitrophenyl)Propane-1,3-Diol (CAS 716-61-0) designed for pharmaceutical antibiotic synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

(R,R)-2-Amino-1-(4-Nitrophenyl)Propane-1,3-Diol is a critical chiral intermediate utilized extensively in the pharmaceutical industry for the synthesis of specific antibiotic compounds. This specialized chemical building block is characterized by its precise stereochemistry, which is essential for ensuring the biological activity and efficacy of the final therapeutic product. Our manufacturing process focuses on maintaining high enantiomeric excess to meet the rigorous demands of modern drug development.

As a dedicated supplier of fine chemical intermediates, we understand the importance of consistency and reliability in your supply chain. This product serves as a foundational component in multi-step organic synthesis pathways, particularly for manufacturers producing complex pharmaceutical agents. The structural integrity of the nitrophenyl group and the diol functionality allows for versatile downstream chemical modifications.

Technical Specifications

Our production facilities adhere to strict quality management systems to ensure every batch meets or exceeds industry standards. The physical and chemical properties are carefully monitored throughout the manufacturing process to guarantee performance in your synthesis reactions.

ParameterSpecification
CAS Number716-61-0
Molecular FormulaC9H12N2O4
Molecular Weight212.203 g/mol
AppearanceWhite to light yellow crystalline powder
Assay (Purity)≥98.0%
Melting Point163-165°C
Loss on Drying≤0.5%
Density1.4±0.1 g/cm3

Quality Assurance and Control

Quality is the cornerstone of our operation. Each production lot undergoes comprehensive analytical testing using advanced instrumentation such as High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. These tests confirm not only the chemical purity but also the stereochemical configuration required for sensitive pharmaceutical applications.

  • Strict batch tracking and traceability systems.
  • Comprehensive Certificate of Analysis (COA) provided with every shipment.
  • Compliance with international safety and quality regulations.
  • Regular internal audits to maintain manufacturing excellence.

Industrial Applications

This intermediate is primarily employed in the synthesis of chloramphenicol and related antibiotic structures. The specific (R,R) configuration is vital for the biological function of the target molecule. Pharmaceutical manufacturers rely on this precursor to ensure the final drug product meets regulatory requirements for potency and safety. It is suitable for use in large-scale industrial production as well as research and development settings.

Storage and Handling

To maintain product stability and integrity, proper storage conditions are essential. The material should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must be tightly sealed when not in use to prevent contamination or degradation. We recommend following standard laboratory safety protocols when handling this chemical, including the use of appropriate personal protective equipment.

We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requirements based on specific logistical needs. Our global distribution network ensures timely delivery to support your production schedules.