(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

Product Overview

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol represents a critical chiral building block within the modern pharmaceutical sector, specifically designed for the synthesis of advanced kinase inhibitors. As a key intermediate in the production of Crizotinib, this compound plays a pivotal role in oncology therapeutics targeting specific genetic mutations. Our manufacturing process ensures high enantiomeric excess, which is essential for maintaining the biological activity and safety profile of the final active pharmaceutical ingredient. We specialize in delivering this complex organic molecule with strict adherence to international quality standards, supporting both research-scale development and large-scale commercial production needs.

The chemical structure features a specific stereoconfiguration at the chiral center, denoted by the (S)-designation. This spatial arrangement is non-negotiable for the downstream coupling reactions required in multi-step synthesis pathways. Our facility utilizes advanced chromatographic purification techniques to achieve assay levels exceeding 98.0 percent. The presence of dichloro and fluoro substituents on the phenyl ring enhances the metabolic stability of the resulting drug molecule, making this intermediate highly valued in modern medicinal chemistry. We understand the complexities involved in handling halogenated aromatic compounds and implement rigorous safety protocols throughout production.

Technical Specifications

Industrial Applications

This specialty chemical is primarily utilized in the pharmaceutical industry for the synthesis of Crizotinib, an important medication used in the treatment of certain types of cancer. The high purity of our intermediate ensures minimal impurity carryover into the final API, reducing the burden on downstream purification steps. Our product is suitable for GMP manufacturing environments and supports novel drug discovery programs targeting ALK receptors. We provide comprehensive technical data to assist process chemists in optimizing reaction conditions.

• High purity ensures minimal impurity carryover
• Suitable for GMP manufacturing environments
• Supports novel drug discovery programs
• Consistent batch-to-batch reproducibility

Quality Assurance and Storage

Quality is the cornerstone of our operation. Every batch of (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol undergoes rigorous testing using HPLC and NMR spectroscopy to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance. For storage, the product should be kept in a cool, ventilated place away from direct sunlight and moisture. We offer flexible packing options, including standard 25 kg drums, and can customize packaging according to specific customer requirements. Our global logistics network ensures timely delivery while maintaining product integrity during transit.