Intermediates

(S)-2-Chloro-1-(2,4-dichlorophenyl)ethan-1-ol

  • CAS No.126534-31-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity chiral intermediate for antifungal synthesis, ensuring optimal reaction efficiency and stereochemical integrity for pharmaceutical manufacturing.

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Product Technical Details

Product Overview

(S)-2-Chloro-1-(2,4-dichlorophenyl)ethan-1-ol is a specialized chiral pharmaceutical intermediate designed for the synthesis of advanced antifungal agents. This compound serves as a critical building block in the production of Luliconazole, demonstrating high stereochemical purity and consistent reactivity. Our manufacturing process adheres to strict international quality standards, ensuring that every batch meets the rigorous demands of modern pharmaceutical synthesis.

The molecular structure features a specific chiral center that is essential for the biological activity of the final drug product. Maintaining the integrity of this stereocenter during downstream processing is paramount, and our production methods are optimized to minimize racemization. This commitment to quality ensures that chemists and process engineers can rely on our material for scalable and efficient synthesis routes.

Key Specifications

We provide comprehensive quality control data with every shipment. The following table outlines the standard physical and chemical properties associated with this intermediate. Custom specifications may be available upon request for large-scale industrial partnerships.

ParameterSpecification
CAS Number126534-31-4
Molecular FormulaC8H7Cl3O
Molecular Weight225.500 g/mol
AppearanceWhite powder
Assay (HPLC)≥98.0%
Loss on Drying≤0.5%
Density1.4±0.1 g/cm3
Boiling Point323.3±37.0 °C at 760 mmHg
Flash Point149.3±26.5 °C

Industrial Applications

This intermediate is primarily utilized in the pharmaceutical sector for the manufacture of antifungal medications. Its high purity profile makes it suitable for multi-step synthesis where impurity carryover could compromise final product safety. Beyond Luliconazole, this chemical structure serves as a valuable reference standard for research and development in organic chemistry.

  • Primary precursor for antifungal drug synthesis.
  • Used in chiral resolution processes.
  • Applicable in medicinal chemistry research.
  • Supports scalable manufacturing protocols.

Quality Assurance and Safety

Our facility implements a robust quality management system. Each production lot undergoes thorough analytical testing, including HPLC analysis and spectral verification. We provide a Certificate of Analysis (COA) with every order, detailing the specific test results for that batch. This transparency allows our clients to maintain their own quality records and regulatory compliance.

Safety is a core component of our operation. While this compound is intended for industrial use, proper handling procedures should always be followed. We recommend storage in a cool, ventilated environment away from incompatible materials. Our packaging is designed to prevent moisture ingress and physical damage during transit.

Packing and Logistics

Standard packaging consists of 25 kg drums, which are suitable for most laboratory and pilot plant requirements. For larger commercial volumes, we offer flexible packaging solutions tailored to customer logistics needs. Our global supply chain ensures timely delivery, supported by experienced freight forwarding partners who understand the nuances of chemical shipping regulations.