(S)-3-Amino-3-phenylpropionic acid
- CAS No.40856-44-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (S)-3-Amino-3-phenylpropionic acid, a key chiral intermediate for advanced pharmaceutical synthesis.
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Product Overview
(S)-3-Amino-3-phenylpropionic acid is a high-value chiral building block widely employed in the synthesis of complex pharmaceutical active ingredients. With a well-defined stereochemistry and robust chemical stability, this compound serves as a critical intermediate in the production of several therapeutically relevant molecules, including antiviral and neurological agents.
Specifications
| Molecular Formula | C9H11NO2 |
|---|---|
| Molecular Weight | 165.189 g/mol |
| Density | 1.2 ± 0.1 g/cm³ |
| Boiling Point | 307.5 ± 30.0 °C at 760 mmHg |
| Flash Point | 139.8 ± 24.6 °C |
| Appearance | Almost white powder |
| Assay (on drying basis) | ≥98.0% |
| Specific Rotation | -6° to -7° |
| Moisture | ≤1.0% |
Industrial Applications
This enantiomerically pure amino acid derivative is primarily utilized as a synthetic intermediate in the manufacture of advanced pharmaceutical compounds. Notably, it plays a pivotal role in the multi-step synthesis of Maraviroc—an FDA-approved CCR5 antagonist used in HIV treatment—and Dapoxetine hydrochloride, a selective serotonin reuptake inhibitor indicated for premature ejaculation. Its rigid phenyl-containing backbone and chiral center enable precise molecular construction in asymmetric synthesis pathways.
- Enables high-yield, stereoselective routes in API development
- Compatible with standard peptide coupling and protection/deprotection protocols
- Supplied in pharma-grade purity with full analytical documentation
Stored in a cool, dry, and well-ventilated environment, the product maintains stability under recommended conditions. Standard packaging is 25 kg per drum, with custom configurations available upon request to meet GMP or research-scale requirements.
