Intermediates

(S)-3-Chloro-1-phenylpropan-1-ol

  • CAS No.100306-34-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity (S)-3-Chloro-1-phenylpropan-1-ol is a critical chiral intermediate used primarily in the synthesis of Dapoxetine hydrochloride.

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Product Technical Details

Product Overview

(S)-3-Chloro-1-phenylpropan-1-ol is a highly specialized chiral organic compound that serves as a critical building block in the synthesis of advanced pharmaceutical agents. As a key intermediate, this substance is characterized by its specific stereochemistry, which is essential for ensuring the biological activity and safety profile of the final active pharmaceutical ingredients (APIs). Our facility produces this compound under strict quality control measures to guarantee high enantiomeric excess and chemical purity, meeting the rigorous demands of modern medicinal chemistry.

The molecular structure features a chloroethyl group attached to a chiral benzyl alcohol backbone, making it a versatile reagent for nucleophilic substitution reactions. This specific configuration allows chemists to construct complex molecular architectures with precision. We understand that consistency in chirality is paramount for regulatory compliance in drug manufacturing, and our production processes are optimized to maintain batch-to-batch reproducibility.

Technical Specifications

Parameter Value
Chemical Name (S)-3-Chloro-1-phenylpropan-1-ol
CAS Number 100306-34-1
Molecular Formula C9H11ClO
Molecular Weight 170.636 g/mol
Appearance Off-white crystalline powder
Assay (Purity) ≥98.0%
Melting Point 58-60 °C
Boiling Point 296.4±20.0 °C
Density 1.149 g/cm³

Industrial Applications

This chemical is predominantly utilized as a precursor in the manufacturing of Dapoxetine hydrochloride, a well-known pharmaceutical compound. Beyond this specific application, (S)-3-Chloro-1-phenylpropan-1-ol finds utility in various organic synthesis pathways where chiral alcohol functionalities are required. Research and development teams in the pharmaceutical sector rely on high-quality intermediates like this to streamline their synthesis routes and reduce impurity profiles in the final drug substance.

  • Primary intermediate for Dapoxetine hydrochloride synthesis.
  • Chiral building block for asymmetric organic synthesis.
  • Reagent for developing neurological therapeutic agents.
  • Component in custom pharmaceutical manufacturing projects.

Quality Assurance and Handling

Quality is the cornerstone of our manufacturing philosophy. Every batch of (S)-3-Chloro-1-phenylpropan-1-ol undergoes comprehensive analytical testing using advanced chromatography and spectroscopy methods. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, identity, and physical properties. Our facility adheres to international safety standards, ensuring that the product is handled and stored under conditions that preserve its stability and integrity.

For storage, we recommend keeping the material in a cool, ventilated area away from direct sunlight and moisture. Proper sealing is essential to prevent hydrolysis or contamination. Our logistics team ensures secure packaging to prevent damage during transit, whether shipping domestically or internationally. We offer flexible packaging solutions to accommodate both laboratory-scale research and large-scale industrial production needs.

Packaging and Supply

Standard packaging includes 25 kg drums, which are designed for safe handling and efficient storage. However, we recognize that different clients have unique requirements. Therefore, we offer custom packaging options upon request. Our global supply chain network allows us to deliver high-quality chemical intermediates to clients worldwide with reliable lead times. Partner with us for a secure supply of critical pharmaceutical intermediates that meet your exact specifications.