(S)-3-Hydroxypyrrolidine Hydrochloride
- CAS No.122536-94-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (S)-3-Hydroxypyrrolidine hydrochloride designed for pharmaceutical intermediate synthesis. Certified quality with global supply capabilities.
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Product Overview
(S)-3-Hydroxypyrrolidine Hydrochloride is a critical chiral building block extensively utilized in the pharmaceutical industry for the synthesis of advanced therapeutic agents. As a key intermediate, this compound plays a pivotal role in the manufacturing process of Darifenacin, a well-known medication used in the management of overactive bladder conditions. Our facility specializes in the production of high-quality chemical intermediates that meet rigorous international standards for purity and consistency.
We understand the importance of stereochemistry in modern drug development. The specific (S)-configuration of this pyrrolidine derivative ensures optimal reactivity and selectivity in downstream synthetic routes. Our manufacturing protocols are designed to maintain strict control over chiral integrity, minimizing impurities and maximizing yield for our global partners.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 122536-94-1 |
| Molecular Formula | C4H10ClNO |
| Molecular Weight | 123.581 |
| Appearance | White powder |
| Assay (HPLC) | 98-102% |
| Melting Point | 104-107°C |
| Specific Rotation | +6.8° to +8.0° |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.5% |
Industrial Applications
This chemical intermediate is primarily employed in the multi-step synthesis of complex pharmaceutical active ingredients. Its primary application lies in the production of Darifenacin hydrobromide and related analogues. The high optical purity provided by our manufacturing process is essential for ensuring the efficacy and safety profile of the final drug product.
Beyond its primary use, (S)-3-Hydroxypyrrolidine Hydrochloride serves as a versatile scaffold in medicinal chemistry research. It is frequently utilized in the development of new neurological therapeutics and other specialized organic synthesis projects where chiral pyrrolidine structures are required. Our technical team supports clients with detailed synthesis routes and process optimization guidance.
Quality Assurance and Packaging
Quality control is the cornerstone of our operation. Every batch of (S)-3-Hydroxypyrrolidine Hydrochloride undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and polarimetry to verify assay and specific rotation. We provide a full Certificate of Analysis (COA) with every shipment, ensuring transparency and compliance with your internal quality standards.
- Produced in GMP-compliant facilities
- Strict control over chiral purity
- Comprehensive impurity profiling
- Stable supply chain management
Standard packaging consists of 25 kg fiber drums, which are designed to protect the product from moisture and light during transit. Custom packaging solutions are available upon request to suit specific logistical requirements. We recommend storing the material in a cool, ventilated area away from direct sunlight to maintain stability over extended periods.
As a global manufacturer, we are committed to supporting the pharmaceutical supply chain with reliable, high-performance chemical intermediates. Contact our sales team for bulk pricing, technical data sheets, and sample availability.
