(S)-4-Benzyl-2-Oxazolidinone

Product Overview

(S)-4-Benzyl-2-Oxazolidinone is a highly specialized chiral building block extensively utilized in the pharmaceutical industry for asymmetric synthesis. As a critical intermediate, this compound plays a pivotal role in the construction of complex molecular architectures, particularly in the manufacturing of advanced therapeutic agents. Our facility produces this oxazolidinone derivative under strict quality control protocols to ensure consistent stereochemical integrity and high chemical purity.

The compound is characterized by its robust stability and reliable reactivity, making it a preferred choice for process chemists engaged in the development of novel drug substances. By leveraging advanced catalytic methods and purification technologies, we deliver a product that meets the rigorous demands of modern medicinal chemistry and large-scale production environments.

Technical Specifications

We adhere to international pharmacopoeia standards and internal quality management systems to guarantee the reliability of every batch. The following table outlines the key physical and chemical parameters verified during our comprehensive quality assurance process.

Industrial Applications

The primary application of (S)-4-Benzyl-2-Oxazolidinone lies in its function as a key intermediate in the synthesis of Agomelatine, a melatonin receptor agonist used in the treatment of major depressive episodes. The chiral center provided by this oxazolidinone ring is essential for establishing the correct stereochemistry required for biological activity.

Beyond this specific pathway, the compound serves as a versatile synthon in organic synthesis. It is frequently employed in Evans auxiliary-type reactions to control diastereoselectivity during alkylation or aldol processes. Researchers and manufacturing teams value this material for its ability to facilitate high-yielding transformations while minimizing the formation of unwanted enantiomers.

Quality Assurance and Storage

Our commitment to quality extends beyond mere specification compliance. Each production lot undergoes rigorous testing using validated analytical methods, including HPLC, NMR, and polarimetry. A Certificate of Analysis (COA) is provided with every shipment to document conformity with agreed-upon standards.

To maintain optimal stability, the product should be stored in a cool, dry environment between 0-6 °C. Containers must remain sealed under an inert gas atmosphere to prevent moisture absorption or oxidative degradation. We offer flexible packaging options, including 25kg cardboard drums, tailored to meet specific logistical requirements and ensure safe global delivery.