Intermediates

(S)-(-)-Trityl Glycidyl Ether

  • CAS No.129940-50-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity (S)-(-)-Trityl Glycidyl Ether (CAS 129940-50-7) designed for pharmaceutical synthesis. Ideal chiral building block for antiviral drug intermediates with stable supply.

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Product Technical Details

Product Overview

(S)-(-)-Trityl Glycidyl Ether is a highly specialized chiral building block extensively utilized in the pharmaceutical industry for the synthesis of complex organic molecules. As a protected epoxy ether derivative, this compound features a trityl group that provides exceptional stability during multi-step synthetic routes. Our manufacturing process ensures high stereochemical purity, making it an essential precursor for the development of nucleoside analogs and antiviral agents. The unique structural configuration allows for precise regioselective ring-opening reactions, which are critical in constructing active pharmaceutical ingredients with specific biological activities.

Produced under strict quality control standards, this chemical intermediate serves as a foundational element in modern medicinal chemistry. The presence of the oxirane ring facilitates versatile functionalization, while the trityl protecting group safeguards the hydroxyl functionality during harsh reaction conditions. This balance of reactivity and stability makes it a preferred choice for process chemists aiming to optimize yield and purity in large-scale production environments. The (S)-configuration is particularly vital for ensuring the correct stereochemistry in the final drug molecule, thereby maximizing therapeutic efficacy and minimizing potential side effects associated with incorrect isomers.

Technical Specifications

ParameterValue
CAS Number129940-50-7
Molecular FormulaC22H20O2
Molecular Weight316.39 g/mol
Purity≥ 98%
AppearanceWhite Powder
Melting Point98-101°C
Boiling Point438.8°C at 760 mmHg
Density1.146 g/cm3
Flash Point164.8°C
Vapor Pressure1.73E-07 mmHg at 25°C

Industrial Applications

This compound is primarily employed in the synthesis of key intermediates for antiviral drug molecules. Its chiral nature is particularly valuable in the production of nucleoside analogs, which are fundamental components in treating various viral infections. The compound acts as a crucial synthon in the construction of sugar moieties found in many therapeutic agents. Beyond antiviral applications, it finds utility in the research and development of novel organic compounds where stereochemistry plays a pivotal role in biological efficacy. Process chemists utilize this ether for its reliable performance in scale-up scenarios.

The robustness of the trityl group allows for diverse downstream transformations without premature deprotection. This reliability reduces waste and improves overall process efficiency, aligning with green chemistry principles increasingly demanded by the global pharmaceutical sector. Our clients leverage this intermediate to accelerate their drug discovery timelines, benefiting from its consistent quality and predictable reactivity profiles in complex synthesis pathways.

Quality Assurance and Supply

  • Consistent batch-to-batch reproducibility ensured by advanced analytical testing.
  • Comprehensive documentation including Certificate of Analysis and Method of Analysis.
  • Secure packaging designed to maintain integrity during international shipping.
  • Technical support available for process optimization and scale-up guidance.
  • Compliance with international regulatory standards for chemical manufacturing.

We are committed to providing reliable supply chains for critical pharmaceutical intermediates. Our facility adheres to rigorous safety and environmental protocols, ensuring that every shipment meets the highest industry standards. For bulk inquiries and custom synthesis requirements, our team is ready to assist with competitive pricing and flexible delivery schedules. Proper storage in a cool, dry place away from incompatible materials is recommended to maintain product stability over extended periods.